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Biochemistry

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JoVE Journal Biochemistry
Un enfoque de grafos de conocimiento para dilucidar el papel de las vías organelares en la enfermedad a través de informes biomédicos
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Un enfoque de grafos de conocimiento para dilucidar el papel de las vías organelares en la enfermedad a través de informes biomédicos

Article DOI: 10.3791/65084-v • 07:35 min • October 13th, 2023
October 13th, 2023 •
1,2,3, 1,3,4, 1, 1, 1, 1, 1, 1, 1, 1, 1,2,3, 3,4, 1,2,3,4,5
1Department of Physiology, UCLA School of Medicine, 2Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, 3NIH BRIDGE2AI Center at UCLA & NHLBI Integrated Cardiovascular Data Science Training Program, UCLA, 4Medical Informatics, University of California at Los Angeles (UCLA), 5Department of Medicine (Cardiology), UCLA School of Medicine

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Se presenta un protocolo computacional, CaseOLAP LIFT, y un caso de uso para investigar las proteínas mitocondriales y sus asociaciones con las enfermedades cardiovasculares descritas en los informes biomédicos. Este protocolo se puede adaptar fácilmente para estudiar los componentes celulares y las enfermedades seleccionadas por el usuario.

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Bioquímica Número 200
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