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Bioengineering

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JoVE Journal Bioengineering
Fremstilling af pulserende polymere mikropartikler, der indkapsler rabiesantigen
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Fremstilling af pulserende polymere mikropartikler, der indkapsler rabiesantigen

Article DOI: 10.3791/65147-v • 07:44 min • May 12th, 2023
May 12th, 2023 •
*1, *2, 1, 3, 2, 1, 2, 1,4
1Department of Bioengineering, Rice University, 2Particles for Humanity, 3IMPACT Technology Development, 4Department of Chemistry, Rice University
* These authors contributed equally

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Denne metode beskriver indkapslingen af rabiesantigenet i bionedbrydelige polymere mikropartikler med strukturelle og materielle egenskaber, der muliggør pulserende frigivelse efter en forudbestemt forsinkelse. Vurdering af enzymbundet immunosorbentassay (ELISA) af antigenet udtaget fra partikelkernen bekræfter tilstedeværelsen af intakt trimerisk rabiesvirusglycoprotein gennem partikelfabrikation.

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Tom værdi udgave 195 Kontrolleret frigivelse pulserende levering poly(mælkesyre-co-glycolsyre) rabies ELISA profylakse efter eksponering vaccination
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