Depression Anxiety Stress

Depression, anxiety, and stress are related but distinct psychological states that influence mood, cognition, physiology, and behavior. Stress arises when perceived demands exceed coping resources, while anxiety involves persistent threat anticipation and depression commonly includes sustained low mood, reduced interest, and diminished motivation. These states can alter attention, sleep, emotional regulation, decision-making, and social behavior through interacting cognitive, behavioral, and physiological processes. Studying their expression in behavior helps researchers assess risk factors, distinguish overlapping symptoms, evaluate psychological and behavioral interventions, and clarify how individuals adapt to challenging environments.

Depression Anxiety Stress - Related Videos

Research

JoVE Journal - Behavior
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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

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Cited by 37 •

2013

This article describes the use of chronic resident intruder social stress as an ethologically relevant paradigm to model postpartum depression and anxiety in lactating rodents.

Research

JoVE EoE - Neuropathology

Inducing Depression-like Behavior in a Mouse via Immobilization Stress

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2025

This video demonstrates the method of inducing chronic stress in a mouse through repeated immobilization, leading to corticosterone release and reduced glutamate receptor activity in neurons, which results in depression-like behavior.

Induction and Evaluation of Depression in Mice Through Chronic Stress Exposure

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2025

Source: Yan, Z., et al. Evaluating the Anti-depression Effect of Xiaoyaosan on Chronically-stressed Mice. J. Vis. Exp. (2019).The video demonstrates the process of establishing a mouse model of chronic stress-induced depression and assessing depressive behaviors. The chronic application of various stressors triggers the release of corticosterone, leading to neuronal over-excitation and eventual neuronal death, which results in depression-like symptoms in the mice.

Research

JoVE Journal - Behavior
Free Sample

Reducing State Anxiety Using Working Memory Maintenance

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Cited by 7 •

2017

This protocol demonstrates how to measure anxiety-potentiated startle during the Sternberg Working Memory paradigm.

Multimodal Behavioral Phenotyping of Stress-Induced Depression-Like States in Drosophila melanogaster

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2026

This protocol provides a framework for assessing stress-induced behavioral changes in Drosophila melanogaster. Combining complementary assays enables the quantification of activity, exploration, and decision-making for individual flies. The approach is flexible and can be adapted to a wide range of studies investigating stress biology, metabolism, and neurobehavioral function.

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