Hidden Platform Trial

A hidden platform trial is a behavioral assay in which an animal learns to locate an escape platform concealed beneath the surface of a pool, making it useful for assessing spatial learning and memory. During repeated trials, the subject uses environmental cues to navigate, while measures such as escape latency, path length, and search strategy indicate how efficiently it acquires and retains the platform location. In behavioral neuroscience, this paradigm helps evaluate cognitive effects of aging, genetic changes, brain injury, or pharmacological treatment, and can distinguish impaired learning from altered motivation or swimming ability.

Hidden Platform Trial - Related Videos

Research

JoVE EoE - Rodent Models

The Water Maze with Platform Relocation: A Method to Assess Working Memory

0 Views •

2023

In this video, we describe the Morris water maze test with platform relocation, a navigational task used to study working memory in rodents.

Education

JoVE Business - Accounting

The Trial Balance

0 Views •

2025

A trial balance is a fundamental financial statement that provides a snapshot of a company's accounts and their balances at a specific point in time. It serves as an essential tool for verifying the accuracy of financial records by ensuring that the total debits equal the total credits. Typically prepared at the end of an accounting period, a trial balance lists all ledger accounts in the order they appear, with debit balances in the left column and credit balances in the right column. The two...

Clinical Trials

0 Views •

2023

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias. There are four phases in a clinical trial. A phase one...

Trial and Error and Algorithm

0 Views •

2025

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light bulb,...

Clinical Trials: Overview

0 Views •

2023

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...

View All Results

FAQs

Related Topics