Spherical Treadmill

A spherical treadmill is a behavioral research apparatus that allows an animal to walk or run on a lightweight, freely rotating ball while remaining in a controlled position. As the animal moves, its leg forces rotate the sphere, and optical sensors or cameras measure ball movement to reconstruct locomotion, orientation, and behavioral responses. Researchers use this system to study navigation, motor control, sensory integration, and activity patterns under controlled visual, olfactory, or other sensory conditions. By combining precise movement tracking with experimental stimuli, spherical treadmills help link neural and sensory processes to behavior in insects and other small animals.

Spherical Treadmill - Related Videos

Education

JoVE Core - Physics

Spherical Coordinates

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2023

Spherical coordinate systems are preferred over Cartesian, polar, or cylindrical coordinates for systems with spherical symmetry. For example, to describe the surface of a sphere, Cartesian coordinates require all three coordinates. On the other hand, the spherical coordinate system requires only one parameter: the sphere's radius. As a result, the complicated mathematical calculations become simple. Spherical coordinates are used in science and engineering applications like electric and...

Research

JoVE Journal - Behavior

Using a Split-belt Treadmill to Evaluate Generalization of Human Locomotor Adaptation

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Cited by 14 •

2017

We describe a protocol for investigating human locomotor adaptation using the split-belt treadmill, which has two belts that can drive each leg at a different speed. We specifically focus on a paradigm designed to test the generalization of adapted locomotor patterns to different walking contexts (e.g., gait speeds, walking environments).

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

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Cited by 93 •

2016

Fatigue is a common, undertreated and frequently poorly-understood symptom in many diseases and disorders. New preclinical assays of fatigue may help to improve current understanding and future treatment of fatigue. To that end, the current protocol provides a novel means of measuring fatigue-like behavior in the mouse.

Actin Treadmilling

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2023

Actin filaments undergo polymerization and depolymerization from either end. The polymerization and depolymerization rates depend on the cytosolic concentration of free G-actins. The polymerization rate is generally higher at the plus or barbed end, while the depolymerization rate is higher at the minus or pointed end. At a steady state, critical concentration describes the concentration of free G-actin monomers at which the polymerization rate at the plus end is equal to that of the...

Research

JoVE Journal - Biology
Free Sample

Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets

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Cited by 19 •

2016

The assembly and positioning of the mitotic spindle depend on the combined forces generated by microtubule dynamics, motor proteins and cross-linkers. Here we present our recently developed methods in which the geometrical confinement of spherical emulsion droplets is used for the bottom-up reconstitution of basic mitotic spindles.

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