Trauma Procedure
Trauma Procedure - Related Videos
10:08
Pseudofracture: An Acute Peripheral Tissue Trauma Model
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Cited by 38 •
2011
Pseudofracture, a reproducible murine model of sterile musculoskeletal trauma, allows for evaluation of late term post-traumatic immune responses. This article describes the procedural execution of the model step by step, including the potential for experimental model combinations to permit study of multiple trauma.
11:14
Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging
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Cited by 11 •
2014
Acute brain trauma is a severe injury that has no adequate treatment to date. Multiphoton microscopy allows studying longitudinally the process of acute brain trauma development and probing therapeutical strategies in rodents. Two models of acute brain trauma studied with in vivo two-photon imaging of brain are demonstrated in this protocol.
07:01
Direct Mouse Trauma/Burn Model of Heterotopic Ossification
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Cited by 68 •
2015
An Achilles tenotomy and burn injury model of heterotopic ossification allows for the reliable study of trauma induced ectopic bone formation without the application of exogenous factors.
09:55
Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
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Cited by 6 •
2018
We present a protocol of personalized script-driven trauma-related imagery and clinical assessments within a comparison design for investigating peritraumatic dissociation (PD), psychophysiological reactions, i.e. heart rate (HR) and skin conductance (SC), and psychological features of often severely traumatized individuals with borderline personality disorder (BPD).
07:18
Focused Assessment with Sonography for Trauma (FAST) Exam: Image Acquisition
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Cited by 7 •
2023
The Focused Assessment with Sonography for Trauma (FAST) exam is a diagnostic point-of-care ultrasound examination used to screen for the presence of free fluid in the pericardium and peritoneum. Indications, techniques, and pitfalls of the procedure are discussed in this article.
FAQs
Standardization makes responses more comparable across individuals or groups by keeping the aversive event or trauma-related condition defined and the observations consistent. Researchers can then distinguish changes associated with the experimental condition from differences caused by how the procedure was delivered. This improves reproducibility and supports clearer comparisons of fear, avoidance, anxiety-like behavior, social interaction, or learning.
Different behavioral measures capture different consequences of a traumatic experience or injury. Fear and avoidance can indicate defensive responses, anxiety-like behavior can reflect altered emotional state, social interaction can reveal changes in interpersonal behavior, and learning measures can show effects on behavioral adaptation. Examining several outcomes provides a broader characterization than relying on a single response.
A study can examine recovery by measuring behavioral responses after the defined aversive condition and comparing how individuals or groups change across the observation period. This allows researchers to characterize both the presence of altered behavior and the pattern of improvement or persistence. Such information helps evaluate whether a potential intervention is associated with more favorable recovery-related outcomes.
Ethical safeguards limit unnecessary harm while allowing researchers to answer the behavioral question under controlled conditions. Monitoring helps identify concerning responses, and humane endpoints provide a predetermined basis for stopping or modifying the procedure when needed. These protections are scientifically important because consistent oversight supports responsible, reproducible studies of traumatic experiences, injury, and stress-related disorders.
A basic workflow establishes a defined aversive event or trauma-related condition, presents it under standardized conditions, and records selected behavioral responses afterward. Researchers then compare observations across individuals or groups and may examine recovery or the effects of a potential intervention. The design should also include monitoring, ethical safeguards, and humane endpoints throughout the study.
Researchers use this approach when they need to characterize how traumatic experiences or injury influence behavior and recovery under controlled conditions. It can support comparisons between individuals or groups, investigation of fear, avoidance, anxiety-like behavior, social interaction, or learning, and evaluation of potential interventions. The resulting behavioral profile can also contribute to studies of stress-related disorders.