Dugesia Tigrina

Dugesia tigrina is a freshwater planarian, or free-living flatworm, widely used to study regeneration, physiology, and biochemical responses in a simple animal model. After injury, pluripotent neoblast stem cells proliferate and differentiate under coordinated molecular signals, restoring missing tissues while maintaining body organization. In biochemistry, D. tigrina supports investigations of enzyme activity, cellular metabolism, oxidative stress, and the effects of environmental chemicals on living tissues. Its accessible anatomy, strong regenerative capacity, and measurable responses help researchers connect molecular processes with tissue repair and organismal health, providing useful context for comparative biology, toxicology, and regenerative research.

Dugesia Tigrina - Related Videos

Research

JoVE Journal - Biology
Free Sample

Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica

0 Views •

Cited by 17 •

2011

An attractive model for studying stem cell differentiation within a live animal is the planarian flatworm. Regeneration is studied by simple amputation experiments that are easily performed in a basic laboratory and are amenable to pharmacological and genetic (in vivo RNAi) manipulation as detailed by protocols in this article.

View All Results

FAQs

Related Topics