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JoVE Journal
Biology

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Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica
 

Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica

Article DOI: 10.3791/3058
August 31st, 2011

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Summary August 31st, 2011

An attractive model for studying stem cell differentiation within a live animal is the planarian flatworm. Regeneration is studied by simple amputation experiments that are easily performed in a basic laboratory and are amenable to pharmacological and genetic (in vivo RNAi) manipulation as detailed by protocols in this article.

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