Needle Array
Needle Array - Related Videos
09:51
Intraosseous Needle Placement
0 Views •
2023
Source: Julianna Jung, MD, FACEP, Associate Professor of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA For unstable patients requiring urgent administration of medications, fluids, or blood products, establishing vascular access quickly is essential. However, there are many factors that can complicate placement of a peripheral intravenous cannula (PIV), and it is extremely common for PIV attempts to fail. PIV placement may be technically challenging in small...
19:40
Design and Use of Multiplexed Chemostat Arrays
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Cited by 108 •
2013
We developed and validated a small-footprint array of miniature chemostats built from readily available parts for low cost. Physiological and experimental evolution results were similar to larger volume chemostats. The ministat array provides a compact, inexpensive, and accessible platform for traditional chemostat experiments, functional genomics, and chemical screening applications.
09:16
Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
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Cited by 7 •
2015
Array CGH for the detection of genomic copy number variants has replaced G-banded karyotype analysis. This paper describes the technology and its application in a diagnostic service laboratory.
08:25
Needle Thoracostomy
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2015
Source: Rachel Liu, BAO, MBBCh, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA A tension pneumothorax is a life-threatening situation in which excess air is introduced into the pleural space surrounding the lung, either through trauma to the chest cavity or as a spontaneous leak of air from the lung itself. Air trapped within the pleural space causes separation of the lung from the chest wall, disrupting normal breathing mechanisms. Pneumothorax may be small without...
08:15
Polymeric Microneedle Array Fabrication by Photolithography
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Cited by 24 •
2015
Here, we present a protocol describing a mold-free fabrication process of the polymeric microneedles by photolithography.
FAQs
Geometry determines how forces distribute across the device and how individual needles penetrate or contact biological material. Needle dimensions influence the local mechanical interaction, while the parallel arrangement coordinates multiple contact points. In bioengineering, these design features help match the interface to localized delivery, sampling, sensing, or tissue-engineering requirements.
Spacing establishes how closely neighboring needles act across a defined area, affecting the distribution of contact and force. Parallel alignment supports coordinated interaction rather than isolated needle placement. Together, these features improve spatial control and allow measurements or material interactions to be repeated across comparable locations within the same region.
Hollow designs provide a structure for localized transport or sampling, whereas solid designs can support direct contact and sensing interactions. The choice depends on whether the array must move material through individual needles or interact with biological material through the needle surfaces. This distinction links device architecture to its intended biological function.
An array distributes multiple interaction sites across a defined region, making repeated measurements possible without relying on a single contact point. This spatial organization can reveal how biological material or tissue responds at different locations. It also improves control over where delivery, sampling, or sensing occurs during an experiment.
Design selection begins with the intended function, such as localized delivery, sampling, sensing, or tissue engineering. Researchers then relate that function to needle geometry, dimensions, spacing, and whether the needles should be hollow or solid. This approach connects microscale structure with the required pattern of contact, transport, or measurement.
Needle arrays support minimally invasive interfaces for drug administration, biosensing, and tissue engineering. They can localize interactions with biological materials while maintaining spatial control over multiple sites. Their value comes from combining microscale device design with biological function, enabling delivery, sampling, sensing, or engineered tissue interactions across a defined area.