Skin Insertion
Skin Insertion - Related Videos
11:39
Peripheral Intravenous Catheter Insertion
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2023
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT The purpose of peripheral intravenous catheter (PIV) insertion is to infuse medications, perform intravenous (IV) fluid therapy, or inject radioactive tracers for special examination procedures. Placing a PIV is an invasive procedure and requires the use of an aseptic, no-touch technique. Common IV venipuncture sites are the arms and hands in adults and the feet in children. According to...
04:07
Generation of Organotypic Full Skin Reconstructs: A Procedure to Establish 3D Skin Model Using Human Skin Samples
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2023
This video describes the detailed protocol for generating in vitro 3D organotypic skin reconstructs to study melanoma progression. This skin model mimics both the architecture and multicellular complexity of organs in vivo.
10:32
Transvaginal Mesh Insertion in the Ovine Model
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Cited by 11 •
2017
This protocol describes mesh implantation in the ovine rectovaginal septum using a single vaginal incision technique, with and without the trocar-guided insertion of anchoring arms.
08:14
Central Venous Catheter Insertion: Subclavian Vein
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2023
Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA Central venous access is necessary in a multitude of clinical situations for hemodynamic monitoring, medication delivery, and blood sampling. There are three veins in the body that are accessed for central venous cannulation: the internal jugular, the subclavian, and the femoral vein. Central venous access via the subclavian vein has several advantages over other possible locations. The subclavian...
05:44
Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
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Cited by 2 •
2025
Skin lesions are common and important features in many rheumatic diseases, and biopsy with pathological analysis plays a critical role in diagnosis. This article provides a detailed overview of the standardized skin biopsy procedure and, using discoid lupus erythematosus as an example, highlights the essential role of dermatopathology in diagnosing rheumatic diseases.
FAQs
Insertion depth determines which tissue region the device reaches, while applied force affects how the device crosses the skin barrier and interacts with surrounding tissue. These variables can alter tissue response, device stability, and the quality of signal measurement or substance delivery. Controlling both helps bioengineers improve placement accuracy and reduce unwanted discomfort or inflammation.
Device geometry and material properties shape the mechanical interaction between the inserted component and skin. Their selection can influence the force required for placement, the stability of the resulting interface, and tissue response after insertion. Bioengineers therefore evaluate these features when developing needles, probes, sensors, electrodes, or biomaterials for reliable access and operation.
A stable device must maintain its intended position and biological interface, but the same insertion conditions can also influence tissue response. Excessive mechanical interaction may contribute to discomfort or inflammation, whereas insufficient control may reduce placement accuracy or performance. Designing the insertion process requires balancing stability, tissue compatibility, and dependable signal or delivery outcomes.
Skin insertion provides a mechanical connection between an engineered component and tissue, allowing devices to perform functions that depend on physical access or contact. In wearable technologies, this can support physiological monitoring or biosensing. In implantable technologies, the interface can support neural monitoring, drug delivery, or other minimally invasive bioengineering applications.
A controlled procedure should account for the intended access location, insertion depth, applied force, device geometry, and material properties. These parameters determine how the component crosses the skin barrier and interacts with tissue. Managing them systematically helps improve placement accuracy, maintain device stability, and support consistent signal acquisition or delivery performance.
Applications include drug delivery, biosensing, neural monitoring, physiological monitoring, and tissue sampling. The appropriate inserted component may be a needle, probe, sensor, electrode, or biomaterial, depending on the intended function. Across these uses, the engineering challenge is to establish effective tissue access while limiting discomfort, inflammation, and loss of device reliability.
Mechanical analysis reveals how insertion depth, force, geometry, and material properties affect the skin-device interaction. Engineers can use this understanding to refine device design and insertion conditions before applying them to monitoring, delivery, sampling, or minimally invasive interfaces. The resulting designs aim for more accurate placement, improved stability, and safer, more reliable operation.