Blood Function

Blood function describes the coordinated roles blood performs as a connective tissue, sustaining homeostasis by transporting materials, defending against threats, and preventing blood loss. Plasma carries nutrients, hormones, gases, and wastes, while red blood cells use hemoglobin to bind oxygen in the lungs and release it to tissues; white blood cells recognize and respond to pathogens, and platelets initiate clot formation when vessels are damaged. Together, these activities regulate temperature, pH, fluid balance, and immune protection across the body. Understanding blood function supports the study of circulation, disease mechanisms, diagnostic testing, and treatments for disorders involving oxygen delivery, infection, or coagulation.

Blood Function - Related Videos

Research

JoVE Journal - Immunology and Infection

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols

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Cited by 5 •

2013

The cell membrane modification of red blood cells (RBCs) with hyperbranched polyglycerol (HPG) is presented. Modified RBCs were characterized by aqueous two phase partitioning, osmotic fragility and complement mediated lysis. The camouflage of surface proteins and antigens was evaluated using the flow cytometry and Micro Typing System (MTS) blood phenotyping cards.

Education

JoVE Core - Anatomy and Physiology

Characteristics and Functions of Blood

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2024

Blood is specialized connective tissue comprising about 8% of the body mass. It has a thick, liquid extracellular matrix that contains cells, dissolved proteins, and electrolytes, making it five times more viscous than water. Blood is warm, around 38°C, and has an alkaline pH ranging from 7.35 to 7.45. The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...

Functional Imaging of Cerebral Blood Flow Using Transcranial Doppler Ultrasound

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2025

Source: Hage, B. D. et. al., Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow. J. Vis. Exp. (2021) This video demonstrates the use of Doppler ultrasound as a functional imaging tool to measure cerebral blood flow velocity, or CBFV in real time. It highlights how frequency shifts in the middle cerebral artery during tasks like breath-holding reveal changes in CBFV, offering insights into brain activity and vascular dynamics.

Research

JoVE Journal - Immunology and Infection
Free Sample

Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells

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Cited by 153 •

2011

Here we describe a method to efficiently expand and purify large numbers of human NK cells and assess their function.

Blood Oxygen Level-Dependent Functional Magnetic Resonance Imaging of the Visual Cortex

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2025

Source: Galenchik-Chan, A., et al. Functional Magnetic Resonance Imaging (fMRI) of the Visual Cortex with Wide-View Retinotopic Stimulation. J. Vis. Exp. (2023). The video demonstrates functional magnetic resonance imaging (fMRI) of the visual cortex to map activity based on blood oxygenation levels. Structural MRI images are acquired as anatomical references, followed by fMRI scans. Visual stimuli are displayed to activate retinotopic neurons in the visual cortex. The increased energy demand...

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