Bursae

Bursae are small, fluid-filled sacs that cushion and separate tissues near joints, helping muscles, tendons, ligaments, skin, and bones move without excessive friction. Each bursa contains a thin layer of synovial fluid and is positioned where repeated pressure or sliding could irritate adjacent structures; movement compresses and releases the sac, distributing mechanical stress across the joint. In biology, bursae illustrate how connective tissues support biomechanics and protect vulnerable surfaces. Their structure and function are also important for understanding bursitis, an inflammation that can cause pain and restricted movement, as well as for studying joint health, injury, and rehabilitation.

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Research

JoVE EoE - Rodent Models

Intact Ovary Harvest from Mouse: A Surgical Procedure to Isolate Complete Ovary from Murine Model

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2025

In this video, we describe a surgical procedure to harvest intact ovary from a mouse model.

Development of Mouse-Derived Organoid Lines from Fallopian Tube Epithelial Cells for High Grade Serous Ovarian Carcinoma Modeling

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2025

This protocol details the development of high-grade serous ovarian carcinoma (HGSOC) mouse models in vitro and in vivo. From the derivation of murine fallopian tube organoids, their genetic modification to recapitulate human HGSOC genetics, and their introduction in the ovarian bursa of syngeneic mice for in vivo development of tumors.

Surgical Trunk Oriented Laparoscopic Right Hemicolectomy (ST-LRH) for Right-Sided Colon Cancer

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2025

This protocol describes Surgical Trunk-oriented Laparoscopic Right Hemicolectomy (ST-LRH), a modified laparoscopic right hemicolectomy designed to optimize vascular management and lymph node dissection, simplify surgical procedures, and improve surgical safety and efficiency.

Neonatal Mouse Ovary Isolation: A Surgical Procedure to Harvest Pair of Ovaries from Neonatal Mouse Model

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2025

In this video, we describe a surgical procedure to isolate ovaries from a neonatal mouse.

Education

JoVE Science Education - Clinical Skills

Using Point of Care Ultrasound to Augment Acquisition of Physical Exam Skills: Knee and Shoulder

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2023

Source: Joseph H. Donroe, Rachel Liu; Yale School of Medicine, USA Point of Care Ultrasound or POCUS is easy to use, has enhanced mobility due to the smaller equipment needed, and may be carried out in a variety of settings. It is also far safer and cheaper than imaging techniques like computer tomography. POCUS can be helpful when certain physical exam findings are difficult to appreciate by palpation, percussion, or auscultation and can facilitate learning elements of the cardiac, pulmonary,...

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