Convalescence

Convalescence is the period of recovery after an illness, injury, surgery, or other physiological stress, during which the body gradually returns to normal function. It involves coordinated processes such as resolution of inflammation, immune system regulation, tissue repair, metabolic recovery, and restoration of physiological homeostasis, with the duration influenced by the condition and the individual’s health. In biology and medicine, studying convalescence helps researchers understand how organisms recover, identify factors that delay healing, and evaluate supportive care, rehabilitation, and follow-up strategies. These insights also inform research on regeneration, chronic disease recovery, and resilience after biological stress.

Convalescence - Related Videos

Research

JoVE Journal - Immunology and Infection

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum

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Cited by 5 •

2018

We describe a simple and easy protocol for measuring antibody dependent enhancement of infection by Zika virus convalescent serum using Dengue virus Reporter Viral Particles.

Assessing Functional SARS-CoV-2 Neutralizing Antibodies

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2026

Source:Kelly Da Costa1, Diego Cantoni1,2, Martin Mayora-Neto1, Tobia Fantoni1,3, Nigel Temperton11Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent.2MRC-University of Glasgow Centre for Virus Research, University of Glasgow.3Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona.This video showcases a neutralization assay measuring serum efficacy in neutralizing SARS-CoV-2 viruses. It involves pseudotyped viruses, serum dilution, and...

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

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2021

The protocol described here outlines a fast and effective method for measuring neutralizing antibodies against the SARS-CoV-2 spike protein by evaluating the ability of convalescent serum samples to inhibit infection by an enhanced green fluorescent protein-labeled vesicular stomatitis virus pseudotyped with spike glycoprotein.

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

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Cited by 11 •

2015

Streptococcus pneumoniae forms discrete non-purulent microscopic lesions in the heart. Outlined is the protocol for a murine model of cardiac microlesion formation. Instruction is provided on microlesion visualization using microscopy, discrimination between early and late microlesions, and methods to detect cardiac remodeling in hearts of convalescent animals.

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