Duodenum
Duodenum - Related Videos
10:10
Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
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2026
This protocol presents robotic duodenum-preserving total pancreatic head resection (R-DPPHRt) for intraductal papillary mucinous neoplasms (IPMNs). A video demonstrates the technique in a patient with main duct-IPMN, highlighting its feasibility as a minimally invasive, organ-preserving alternative to pancreaticoduodenectomy.
08:32
Efficient Generation of Pancreas/Duodenum Homeobox Protein 1+ Posterior Foregut/Pancreatic Progenitors from hPSCs in Adhesion Cultures
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2019
Here, we present a detailed protocol to differentiate human pluripotent stem cells (hPSCs) into pancreas/duodenum homeobox protein 1+ (PDX1+) cells for the generation of pancreatic lineages based on the non-colony type monolayer growth of dissociated single cells. This method is suitable for producing homogenous hPSC-derived cells, genetic manipulation and screening.
03:34
Laparoscopic Duodenum-Preserving Pancreatic Head Resection via Inferior Infracolic Approach: A Surgical Approach for Benign Lesions
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2024
This article provides a whole technical process of laparoscopic duodenum-preserving pancreatic head resection via an inferior infracolic approach. This is a surgical approach for benign tumors without intraoperative fluorescence image guidance.
02:05
Intraduodenal Cannulation in a Rat Model for Immunopathology Studies
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2025
This video demonstrates intraduodenal cannulation in a rat model. After anesthetizing the rat, the duodenum is located and a small puncture is created. A J-shaped cannula with a beveled tip is carefully inserted and secured, and the incision is closed. The cannulated rat model enables intra-intestinal infusion for immunopathology studies.
06:43
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
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2026
This video case report demonstrates the unique management of a duodenal gastrointestinal stromal tumor with a rare, understudied, exon 8 KIT mutation. Neoadjuvant therapy resulted in a 30% reduction in tumor size, making the patient a candidate for a robotic-assisted duodenal sleeve resection instead of the more morbid pancreaticoduodenectomy.
FAQs
Bicarbonate helps neutralize the acidity of chyme arriving from the stomach. This chemical adjustment creates conditions in which digestive enzymes can act on carbohydrates, proteins, and fats within the duodenum. The process links stomach emptying with intestinal digestion and helps prepare partially digested material for subsequent nutrient uptake.
The duodenum receives bile from the liver and gallbladder together with secretions from the pancreas. These inputs join the material arriving from the stomach and support the breakdown of carbohydrates, proteins, and fats. Their coordinated delivery makes the duodenum an important meeting point between gastric digestion and later intestinal processing.
Mucosal folds and villi increase the internal surface area of the duodenum. A larger surface supports more effective contact between digested material and the absorptive lining, helping nutrients move into the body after chemical breakdown. This structural arrangement connects duodenal anatomy with its role in nutrient uptake rather than serving only as a shape characteristic.
After receiving stomach contents and digestive secretions, the duodenum helps organize the transition from chemical digestion to nutrient absorption farther along the intestine. Its activities connect neutralization, enzymatic breakdown, and movement of processed material with downstream intestinal processes. Studying this coordination clarifies how separate gastrointestinal regions contribute to one continuous digestive sequence.
Impaired pancreatic or biliary function can disrupt the secretory inputs that the duodenum requires for normal digestion. Examining these relationships helps researchers connect organ-level dysfunction with changes in carbohydrate, protein, and fat breakdown. The duodenum therefore provides a useful biological context for understanding how digestive organs depend on one another.
The duodenum is relevant to disorders that include inflammation and ulceration, as well as problems associated with impaired pancreatic or biliary function. Studying its anatomy and physiology helps relate these conditions to acid handling, digestive secretions, nutrient uptake, and intestinal coordination. This makes the region important in both basic biology and gastrointestinal research.