Hormonal Cycle Assessment

Hormonal cycle assessment is the systematic measurement and interpretation of hormone fluctuations across a biological cycle, helping characterize reproductive physiology and endocrine function. It typically uses timed blood, urine, or saliva samples to track hormones such as follicle-stimulating hormone, luteinizing hormone, estrogen, and progesterone, whose changing concentrations reflect feedback within the hypothalamic-pituitary-gonadal axis and mark cycle phases. In biology, this approach supports evaluation of ovulation, menstrual-cycle patterns, fertility, and hormonal disorders. It also provides researchers with a framework for comparing endocrine responses, studying reproductive health, and assessing how physiological or environmental factors influence cyclic hormone regulation.

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JoVE Core - Anatomy and Physiology

Hormonal Regulation of the Menstrual Cycle

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2024

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins. At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.

Hormonal Control of the Ovarian Cycle

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2024

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction. Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...

Types of Hormones

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2019

Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells. Steroid hormones are derived from cholesterol and are lipophilic in nature. This allows them to readily traverse the lipid-rich cell membrane to bind to their intracellular receptors in the cytoplasm or nucleus. Once bound, the cytoplasmic hormone-receptor complex translocates to the nucleus.

Hormonal Regulation

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2019

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.

Plant Hormones

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2020

Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands. Instead, plant hormones are often produced in regions of active growth, like the tips of roots and shoots. Additionally, even very low concentrations of plant hormones can have a profound effect on growth and development processes.

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