Nanojet Two

A programmable plunger drives fluid through a fine glass micropipette, providing controlled delivery of extremely small liquid volumes. This mechanism helps researchers regulate the amount introduced into an individual cell or embryo rather than applying a reagent broadly. Consistent plunger-driven delivery is especially valuable when experimental effects depend on the quantity of genetic material, tracer, drug, or other reagent received.

The fine glass micropipette provides a narrow route into a selected specimen, supporting localized delivery while limiting physical disruption. Its use allows researchers to manipulate individual cells or embryos that may respond poorly to bulk treatment. This targeted access connects the injected reagent with a specific biological specimen, making subsequent observations of development, cell behavior, or gene function more interpretable.

Standardizing nanoliter-scale delivery reduces variation in the volume introduced from one specimen to another. With a programmable plunger and controlled fluid passage, researchers can apply a more consistent treatment during repeated microinjections. Greater consistency helps distinguish biological differences from delivery-related variation, strengthening comparisons across specimens and supporting more reproducible studies of disease mechanisms, development, or gene function.

The instrument can deliver genetic material, tracers, drugs, or other reagents into selected biological specimens. The appropriate material depends on the experimental question: genetic material can support studies of gene function, tracers can help examine biological processes, and drugs can be used to investigate cellular or disease-related responses. The same delivery approach therefore supports several kinds of biological manipulation.

A researcher selects the cell or embryo to be manipulated, loads the intended liquid reagent for delivery, and uses the programmable plunger to drive it through a fine glass micropipette. The controlled injection is directed into the selected specimen, after which researchers can study resulting changes in development, gene function, cell behavior, or disease mechanisms.

Targeted microinjection is useful when researchers need to manipulate individual cells or embryos rather than expose an entire sample to the same treatment. Nanojet Two supports this approach by delivering very small, controlled volumes while limiting physical disruption. It is therefore relevant to experiments requiring specimen-level control, including investigations of development, gene function, cell behavior, and disease mechanisms.