Odor Stimulation
Odor Stimulation - Related Videos
06:41
Testing for Odor Discrimination and Habituation in Mice
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Cited by 66 •
2015
This manuscript describes a protocol to examine the olfactory system of rodents. The olfactory habituation/dishabituation test will allow investigators to determine whether a mouse habituates to a repeatedly presented odor and whether the mouse demonstrates dishabituation when presented a novel odor.
02:53
Electrophysiological Recordings from Drosophila Sensilla in Response to Volatile Odorants
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2025
In this video, a live Drosophila fly is mounted in a tube for electrophysiological studies. Electrodes are positioned at the base of the sensillum to record specific neuronal responses to pheromones with the fly's olfactory receptor neurons.
02:52
Real-Time Monitoring of Odorant Receptor Activation in Recombinant Cells
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2025
Source: de March, C. A. et. al., Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase. J. Vis. Exp. (2019)This video demonstrates the method to monitor the real-time activation of odorant receptors in recombinant mammalian cells using luminescence measurement. Odorant binding triggers G-protein activation and cAMP production, activating glosensor proteins that emit luminescence upon substrate binding, providing a quantitative measure of receptor response.
07:49
Electrophysiological Recording from Drosophila Trichoid Sensilla in Response to Odorants of Low Volatility
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Cited by 16 •
2017
The overall goal of this protocol is to demonstrate how to present odorants of low volatility for single-sensillum recording from Drosophila olfactory receptor neurons that respond to long-chain cuticular pheromones.
13:31
High-resolution Quantification of Odor-guided Behavior in Drosophila melanogaster Using the Flywalk Paradigm
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Cited by 9 •
2015
The automated tracking system Flywalk is used for high-resolution quantification of odor-guided behavior in Drosophila melanogaster.
FAQs
After airborne odorants dissolve in nasal mucus, they interact with receptors located on olfactory sensory neurons. This receptor activation starts intracellular signaling, meaning chemical events inside the neuron that convert odor information into electrical impulses. The impulses provide the nervous system with a signal that can be transmitted onward for further processing and response.
The olfactory bulb receives electrical impulses generated by olfactory sensory neurons and serves as an early destination for olfactory information. From there, signals reach higher brain regions where odor-related information can be processed in relation to behavior, memory, and physiological responses. This pathway links molecular detection in the nose with broader biological effects.
Controlled odor stimulation gives researchers a defined way to examine how chemical information becomes organized as neural activity. By observing responses from the olfactory system under controlled conditions, studies can investigate neural coding, the representation of odor information by patterns of nervous-system activity. This helps connect receptor activation with perception, behavior, and other biological responses.
In biological research, odor stimulation is used as a controlled sensory input while investigators examine olfactory-system activity or resulting responses. The approach can support studies of sensory transduction, the conversion of chemical signals into electrical impulses, as well as neural coding and behavior. Its value comes from linking a defined environmental cue to measurable biological outcomes.
Researchers can use odor stimulation to examine behaviors influenced by environmental chemical cues, including animal communication, feeding, and navigation. These studies explore how organisms detect relevant odors and translate that information into actions or responses. The method therefore connects olfactory mechanisms with ecologically meaningful behavior rather than examining sensory signaling in isolation.
Odor stimulation provides a way to study how olfactory signals relate to memory and physiological responses, because odor information is transmitted from sensory neurons through the olfactory bulb to higher brain regions. It can also support investigations of disease-related changes in olfactory function, helping researchers examine altered responses within a broader biological and neural context.