Subarachnoid Space
Subarachnoid Space - Related Videos
04:35
Establishing a Subarachnoid Hemorrhage Rat Model Induced by Autologous Blood Injection
0 Views •
2025
This video demonstrates the procedure for establishing a subarachnoid hemorrhage rat model. An anesthetized rat is implanted with probes to measure intracranial pressure and cerebral blood flow. The target site is identified, and the needle is inserted at a pre-chiasmatic position. Autologous blood is then injected into the subarachnoid space, increasing intracranial pressure and decreasing cerebral blood flow, establishing the model.
04:43
Induction of a Subarachnoid Hemorrhage in a Mouse Model through Endovascular Perforation
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2025
The video demonstrates the induction of subarachnoid hemorrhage via endovascular perforation in a mouse model. An incision is made in the neck region of the anesthetized mouse to access the common carotid artery and its bifurcation. A filament is inserted through the arteries to perforate an intracranial artery branch, inducing subarachnoid hemorrhage.
07:03
A Low Mortality Rat Model to Assess Delayed Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage
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Cited by 22 •
2013
Aneurysmal subarachnoid hemorrhage (SAH) is bleeding that occurs into the subarachnoid space when an aneurysm ruptures. While the morbidity and mortality from this event has been on a decline due to improved treatment approaches, the risk of vasospasm after subarachnoid hemorrhage continues to be the same as it was several years ago. The importance of establishing a comprehensive and reproducible animal model to identify initiating events of cerebral vasospasm has been the focus of research...
07:54
In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen
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Cited by 16 •
2012
Simple and reproducible procedures are described for making three structurally distinct collagen assemblies from a common commercially available Type I collagen monomer. Native type, fibrous long spacing or segmental long spacing collagen can be constructed by varying the conditions to which the 300 nm long and 1.4 nm diameter monomer building block is exposed.
01:25
Space Curves
0 Views •
2026
A space curve describes the path followed by a particle moving through three-dimensional space. Unlike plane curves, which are confined to two coordinates, space curves require three coordinate functions. If t is a parameter, the position of the particle is represented by the vector function\begin{equation*}\mathbf{r}(t)=\langle x(t),y(t),z(t)\rangle,\end{equation*}where x(t), y(t), and z(t) are differentiable functions of t. As t varies over an interval, the endpoints of the position vectors...
FAQs
CSF provides buoyancy, which helps support nervous tissue, and cushions the brain and spinal cord against physical stress. It also contributes to a stable local environment around these structures. Because CSF circulates through the subarachnoid space, its effects extend around both major regions of the central nervous system rather than remaining confined to one location.
Delicate connective-tissue trabeculae and major blood vessels are structural components of the subarachnoid space. Their presence helps explain why this compartment is more than a simple reservoir for CSF: it also contains anatomical elements associated with the nervous system and its circulation. These relationships are important when studying normal anatomy and changes caused by disease.
CSF circulation allows the fluid to move through the space surrounding the brain and spinal cord. This movement supports the distribution of buoyancy, cushioning, and environmental stability across nervous tissue. Studying CSF dynamics therefore helps researchers connect the anatomy of the subarachnoid space with broader questions about how the central nervous system is maintained.
Lumbar puncture is clinically connected to the subarachnoid space because CSF occupies this compartment around the spinal cord. Understanding that relationship helps explain why the procedure is used when CSF must be accessed or examined. The anatomy also provides context for interpreting CSF-related investigations in medicine without treating the surrounding tissues as separate from the sampled fluid.
Intrathecal delivery places substances in relation to the CSF-containing compartment surrounding the central nervous system. Their distribution is therefore studied in the context of CSF movement and the anatomy of the subarachnoid space. This makes the compartment relevant to research on how administered substances may be distributed around the brain and spinal cord.
Bleeding into this compartment produces a subarachnoid hemorrhage, demonstrating that the space's anatomy has direct neurological consequences. Blood enters an area normally associated with CSF, trabeculae, and major vessels, altering the local environment around nervous tissue. This condition links structural anatomy with disease mechanisms and explains why the subarachnoid space matters in neurological medicine.