Thermo Reversible Crosslinking
Thermo Reversible Crosslinking - Related Videos
07:02
The Preparation and Properties of Thermo-reversibly Cross-linked Rubber Via Diels-Alder Chemistry
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Cited by 3 •
2016
A simple two-step approach involving rubber modification and cross-linking yields fully reworkable, elastic rubber products.
03:47
Crosslinking Neuronal Surface Proteins in the Mouse Brain using a Chemical Crosslinking Assay
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2025
This video demonstrates the crosslinking of neuronal surface proteins using Bis-sulfosuccinimidyl suberate or BS3. Isolated and chilled mouse brain is sectioned coronally. The desired region is extracted from the sections, minced, and treated with BS3. BS3 crosslinks surface proteins like GABA receptors, leaving internal proteins unaltered. The reaction is quenched with glycine before processing the samples for further analysis.
09:09
Synthesis of Poly(N-isopropylacrylamide) Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
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Cited by 3 •
2016
We present a protocol to synthesize Janus microhydrogels composed entirely of the same base material, poly(N-isopropylacrylamide) (PNIPAAm), with a clearly compartmentalized structure base on the phase separation of a supersaturated NIPAAm monomer solution. The synthesized Janus microhydrogels show unique properties such as anisotropic thermo-responsiveness and organophilic/hydrophilic loading capability.
11:15
Nanosponge Tunability in Size and Crosslinking Density
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Cited by 1 •
2017
This article describes a process for tuning the size and crosslinking density of covalently crosslinked nanoparticles from linear polyesters containing pendant functionality. By tailoring synthesis parameters (polymer molecular weight, pendant functionality incorporation, and crosslinker equivalents), a desired nanoparticle size and crosslinking density can be achieved for drug delivery applications.
09:12
Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering
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Cited by 2 •
2016
A method for the functionalization of carbon nanotubes with structure-tunable polymeric encapsulation layers and structural characterization using small-angle neutron scattering is presented.
FAQs
Temperature changes the balance between polymer chains, strengthening or weakening associations that hold the network together. Depending on the material, these associations may arise from hydrogen bonding, hydrophobic interactions, crystalline domains, or reversible covalent bonds. As those connections form or dissociate, the network can move between more structured and more mobile states, changing its mechanical behavior.
Each type of association responds to temperature through a different molecular interaction, so the resulting network behavior depends on which domains dominate. Hydrogen-bonded and hydrophobic associations can be disrupted or promoted as conditions change, while crystalline domains provide temperature-sensitive ordered regions. These differences influence how readily a material changes stiffness, flow, durability, or recoverability.
Reversible covalent bonds provide molecular connections that can form and dissociate with temperature changes, alongside noncovalent associations. Their reversibility allows the network to reorganize rather than remain permanently fixed. In material design, this behavior supports temperature-controlled reshaping and recovery while preserving the broader ability to adjust physical properties through changes in molecular connectivity.
Heating or cooling can be used to shift the material between states with different degrees of molecular association. A temperature change may promote gelation, disrupt a network, enable processing, or support recovery of an earlier form. Repeated control of these transitions connects a practical temperature cycle with changes in stiffness, flow, and network structure.
The approach supports responsive hydrogels, coatings, adhesives, and recyclable materials because their polymer networks can be adjusted through temperature. Hydrogels can undergo controllable gelation, while coatings and adhesives can take advantage of changes in network behavior during use or processing. Recyclable materials benefit from connections that can be disrupted and re-established rather than remaining permanently fixed.
Thermoreversible crosslinking links molecular-scale interactions to observable changes in stiffness, flow, and durability. Chemists can therefore design polymer networks whose physical state responds to temperature rather than remaining static. This relationship is useful when a material must be processed, reshaped, recovered, or made responsive while retaining a controllable network structure.