Core Temperature

Core temperature is the temperature of the body’s internal tissues and organs, reflecting the balance between metabolic heat production and heat loss. In clinical physiology, the hypothalamus regulates this balance by integrating thermal signals and coordinating responses such as sweating, vasodilation, vasoconstriction, and shivering to maintain temperature within a narrow range. Clinicians assess core temperature using measurements from sites such as the esophagus, rectum, bladder, or pulmonary artery, depending on the patient’s condition and monitoring needs. Accurate assessment supports the recognition and management of fever, hypothermia, infection, anesthesia-related temperature changes, and thermoregulatory disorders.

Core Temperature - Related Videos

Research

JoVE EoE - Rodent Models

Surgical Implantation of Temperature Telemetric Monitoring System in Mouse Model: A Surgical Procedure to Implant Temperature Telemetric Device to Measure Mouse Core Body Temperature

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2025

In this video, we describe a surgical procedure to implant a temperature telemetric device in a mouse model to continuously measure its core body temperature.

Research

JoVE Journal - Medicine
Free Sample

Implantation of Radiotelemetry Transmitters Yielding Data on ECG, Heart Rate, Core Body Temperature and Activity in Free-moving Laboratory Mice

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Cited by 56 •

2011

A surgical technique for implantation of commercially available telemetry transmitters used for continuous measurement of biopotential (one-lead ECG), heart rate, core body temperature and locomotor activity in freely moving mice is shown. Recommendations and protocols for post-operative care and pain relief, improving recovery, well being and survival rate are also presented.

Education

JoVE Core - Molecular Biology

The Nucleosome Core Particle

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2020

Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins. The paradox Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...

Visualizing the Effect of pH on Solubilization of the Influenza A Viral Core

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2026

Source: Stauffer, S. et al., In Vitro Disassembly of Influenza A Virus Capsids by Gradient Centrifugation. J. Vis. Exp. (2016)This video demonstrates the effect of pH on the solubilization of influenza A viral cores. Gel electrophoresis and protein staining reveal the progressive disassembly of the core structure under acidic conditions.

Using an Ingestible Telemetric Temperature Pill to Assess Gastrointestinal Temperature During Exercise

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Cited by 32 •

2015

This study describes an accurate, reliable and non-invasive technique to continuously measure gastrointestinal temperature during exercise. The ingestible telemetric temperature pill is suitable to measure gastrointestinal temperature in laboratory settings as well as in field based settings.

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