Channel Diameter Tuning

Channel diameter tuning is the deliberate adjustment of a channel’s internal width to control how fluids, particles, or signals move through an engineered system. In fluidic devices, diameter changes alter flow resistance, pressure drop, velocity, and transport behavior; smaller channels generally increase resistance, while larger channels permit greater throughput under comparable conditions. Engineers use this design variable in microfluidics, piping, heat exchangers, and porous materials to balance efficiency, mixing, heat transfer, and system stability. Careful tuning can improve device performance, reduce energy demands, and support precise control of processes ranging from sample handling to industrial fluid transport.

Channel Diameter Tuning - Related Videos

Research

JoVE Journal - Chemistry

Tuning a Parallel Segmented Flow Column and Enabling Multiplexed Detection

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Cited by 1 •

2015

Here, we present a protocol for the operation and tuning of parallel segmented flow chromatography columns to enable multiplexed detection.

Mass Cytometry: Protocol for Daily Tuning and Running Cell Samples on a CyTOF Mass Cytometer

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Cited by 48 •

2012

The steps necessary for daily tuning and optimization of the performance of a CyTOF mass cytometer are described. Comments on optimal sample preparation and flow rate are...

Education

JoVE Core - Biology

Ion Channels

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2019

The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange. Ion channels are specialized integral membrane proteins on the plasma membrane that allow specific...

Research

JoVE Journal - Engineering
Free Sample

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

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Cited by 18 •

2013

A methodology for preparing solid-state nanopores in solution for biomolecular translocation experiments is presented. By applying short pulses of high electric fields, the nanopore diameter can be controllably enlarged with subnanometer precision and its electrical noise characteristics significantly improved. This procedure is performed in situ using standard laboratory equipment under experimental conditions.

Propeller Characterization: Variations in Pitch, Diameter, and Blade Number on Performance

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2023

Source: Shreyas Narsipur, Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC A propeller is a twisted airfoil, where the angle of the chord changes with respect to the location, along the radial station, as shown in Figure 1. Propellers are widely used in aircraft and watercraft propulsion systems thereby necessitating detailed characterizations of propellers to design high performance vehicles. Figure 1. Chord, thickness, and pitch at a radial station. One of...

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