Fermentation Process

The fermentation process is a biological and biochemical pathway in which microorganisms or cells convert organic substrates into products such as organic acids, alcohols, and gases, often without oxygen. During fermentation, microbes break down carbohydrates through glycolysis and regenerate essential electron carriers by transferring electrons to organic molecules, allowing metabolism to continue under anaerobic conditions. In environmental sciences, this process supports wastewater treatment, organic waste stabilization, and the production of renewable fuels and chemicals. Understanding fermentation helps researchers optimize microbial communities, control environmental conditions such as pH and temperature, and improve resource recovery while reducing waste and greenhouse-gas emissions.

Fermentation Process - Related Videos

Education

JoVE Core - Biology

Fermentation

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2019

Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism. Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...

Research

JoVE EoE - Bacterial Growth and Techniques

Microaerobic Fermentation of Bamboo Hydrolysate by Klebsiella pneumoniae

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2025

Source: Wei, D., et al., Production of Chemicals by Klebsiella pneumoniae Using Bamboo Hydrolysate as Feedstock. J. Vis. Exp. (2017)This video demonstrates the microbial conversion of bamboo-derived sugars into 2,3-butanediol by culturing Klebsiella pneumoniae in a hydrolysate-based medium under microaerobic and mildly acidic conditions.

Research

JoVE Journal - Biology
Free Sample

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

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Cited by 14 •

2016

A production protocol is described for the small-scale production of probiotic fermented dairy drink with the aid of a novel bacterial starter culture.

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol

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Cited by 4 •

2016

Adaptive evolution and isolation techniques are described and demonstrated to yield derivatives of Scheffersomyces stipitis strain NRRL Y-7124 that are able to rapidly consume hexose and pentose mixed sugars in enzyme saccharified undetoxified hydrolyzates and to accumulate over 40 g/L ethanol.

Microbial Fermentation

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2025

Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...

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