Equine Respiratory Disease
Equine Respiratory Disease - Related Videos
01:29
Respiratory Syncytial Virus Disease
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2026
Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
09:24
Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease
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Cited by 8 •
2017
This paper introduces a method for repeated measurements of ventilation and respiratory muscle activity in a freely behaving amyotrophic lateral sclerosis (ALS) mouse model throughout disease progression with whole-body plethysmography and electromyography via an implanted telemetry device.
09:41
Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
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Cited by 3 •
2024
This paper describes a method of abdominal wall closure using tension and apposition sutures in horses undergoing ventral midline laparotomies. It also describes methods for prevention and management of postoperative incisional complications, such as bandaging, negative pressure therapy, and in case of wound breakdown, the application of retention sutures.
04:36
A Simple Microaspiration Technique for Isolating Somatic Cells from Cryopreserved Equine Semen as Nuclear Donors for Cloning
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2025
This protocol presents a simple microaspiration technique to isolate viable somatic cells (SCs) from cryopreserved equine semen. Unlike traditional approaches, this technique avoids long in vitro cultures and overcomes sperm contamination, enabling immediate use in somatic cell cloning.
04:25
Harvesting Articular Cartilage From Joints of an Equine Donor: A Surgical Procedure to Isolate Vascular Connective Tissue From Cadaveric Joints of an Equine Donor
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2025
In this video, we demonstrate the extraction of articular cartilage from an equine cadaveric joint. The isolated articular cartilage can be used for further downstream analysis.
FAQs
Mucociliary clearance normally helps remove material from the airways. When infection, allergens, or environmental irritants disrupt this process, mucus can accumulate and remain in contact with airway tissues for longer periods. That change can intensify inflammation, promote coughing, and interfere with gas exchange, making clearance an important mechanism when evaluating respiratory disease progression and clinical impact.
Both innate and adaptive immune responses become relevant when airway tissues encounter respiratory pathogens or other inflammatory triggers. Their activation helps explain why disease can involve airway inflammation, mucus accumulation, and altered respiratory function. Immune profiling adds information beyond clinical signs by helping characterize how the host response relates to disease cause and progression.
Viral or bacterial pathogens, allergens, and environmental irritants can all disturb airway function and activate inflammatory responses. Consequently, coughing or impaired gas exchange does not by itself identify the underlying cause. Distinguishing these possibilities requires combining clinical examination with pathogen detection, cytology, and immune profiling rather than relying on a single observed sign.
Environmental irritants can disrupt airway defenses and contribute to inflammation even when a pathogen is not identified. This makes stable management relevant alongside medical evaluation. Reducing conditions that promote airway irritation supports respiratory health, while clinical assessment and laboratory characterization help determine whether environmental exposure, infection, or a combination of factors is contributing to disease.
These approaches provide complementary evidence rather than interchangeable results. Clinical examination characterizes the horse's respiratory condition, pathogen detection helps investigate infectious causes, cytology contributes cellular information, and immune profiling describes the host response. Used together, they help distinguish causes and characterize disease progression, supporting more targeted decisions about prevention and treatment.
They are particularly useful when clinical signs alone cannot distinguish an infectious process from inflammation associated with allergens or environmental irritants. Pathogen detection addresses whether a relevant infectious cause can be identified, whereas immune profiling helps characterize the horse's response. This combined information strengthens investigation of host-pathogen interactions and disease progression.
Prevention relies on more than one strategy because respiratory disease may involve infectious agents as well as environmental triggers. Vaccination supports prevention of relevant infections, biosecurity helps limit infectious spread within equine populations, and stable-management practices address irritating conditions. Together, these measures complement diagnosis and treatment while supporting animal health, performance, and welfare.