Magnetic Holder
Magnetic Holder - Related Videos
07:55
An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering
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Cited by 4 •
2019
A novel sample holder for macromolecular X-ray crystallography along with a suitable handling protocol is presented. The system allows crystal growth, crystal soaking and in situ diffraction data collection at both, ambient and cryogenic temperature without the need of any crystal manipulation or mounting.
10:04
Magnetic Fields
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2023
Source: Yong P. Chen, PhD, Department of Physics & Astronomy, College of Science, Purdue University, West Lafayette, IN Magnetic fields can be generated by moving charges, such as an electrical current. The magnetic field generated by a current can be calculated from the Maxwell equation. In addition, magnetic objects such as bar magnets can also generate magnetic fields due to microscopic dynamics of charges inside the material. Magnetic fields will exert magnetic force on other moving...
03:02
Colors and Magnetism
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2020
Color in Coordination Complexes When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human eye.
05:41
Live-Cell Imaging of Intact Ex Vivo Globes Using a Novel 3D Printed Holder
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Cited by 2 •
2022
The present work describes a novel experimental protocol that utilizes a 3D printed holder to enable high-resolution live cell imaging of enucleated globes. Through this protocol, the cellular calcium signaling activity in wounded corneal epithelium from ex vivo globes can be observed in real time.
10:41
Characterization of Magnetic Components
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2023
Source: Ali Bazzi, Department of Electrical Engineering, University of Connecticut, Storrs, CT. The objective of this experiment is to achieve hands-on experience with different magnetic components from design and material perspectives. This experiment covers B-H curves of magnetic material and inductor design through identifying unknown design factors. The B-H curve of a magnetic element, such as an inductor or transformer, is a characteristic of the magnetic material forming the core around...
FAQs
The separation depends on two linked events: antibody-coated magnetic beads bind the intended cells, microorganisms, or biomolecules, and the holder concentrates those beads against the tube wall. Once the target-bearing beads are retained, unbound liquid can be removed or exchanged without transferring the entire sample. This arrangement supports selective recovery while limiting unnecessary handling.
The antibody coating provides the recognition step that links magnetic particles to a selected target. Depending on the assay, that target may be an immune-cell population, infectious agent, or pathogen-associated biomolecule. The magnetic response then makes the bead-bound material physically manageable, allowing researchers to concentrate, wash, enrich, or purify the selected fraction for later analysis.
Magnetic retention keeps the captured material positioned while the surrounding liquid is exchanged, reducing the need to move the sample between containers. Fewer manual transfer steps can improve recovery and contribute to more reproducible preparation. These benefits matter when downstream detection, characterization, or molecular testing depends on preserving and concentrating the recovered target.
A typical workflow begins by allowing antibody-coated magnetic beads to contact the sample so target cells, microorganisms, or biomolecules can associate with them. The holder then concentrates the bead-bound material at the tube wall. Researchers remove or exchange unbound liquid, perform washing or enrichment as needed, and retain the prepared fraction for downstream analysis.
In immunology and infection research, the approach can be applied to samples containing immune-cell populations, infectious agents, or pathogen-associated targets. The selected material may be concentrated from a broader sample and separated from unbound components. This makes the preparation useful when subsequent assays require detection, characterization, or molecular testing of a defined target fraction.
After capture, washing, enrichment, or purification, the prepared material can support several forms of downstream analysis. Researchers may use it for detection of a target, characterization of recovered cells or infectious agents, or molecular testing of pathogen-associated material. The value lies in producing a more manageable and concentrated sample while reducing handling-related losses during preparation.