Aortic Excision
Aortic Excision - Related Videos
12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Cited by 4 •
2017
Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.
09:12
Aortic Ring Assay
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Cited by 42 •
2009
Angiogenesis, the sprouting of blood vessels from pre-existing vasculature, is associated with both natural and pathological processes. Here we demonstrate an aortic ring assay that allows angiogenic potentiators and inhibitors to be directly added to aortic rings in culture. Sprouting and neovessel outgrowth can be determined by inspecting the aortic rings over a period of 6-12 days.
01:54
Base Excision Repair
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2020
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template. The first step of...
03:37
Porcine Heart Excision: A Protocol to Extract Porcine Heart for Cardiac Transplant
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2025
In this video, we describe a step-by-step protocol to extract the heart from a porcine model for cardiac transplantation.
10:12
Near-infrared Fluorescence Imaging of Abdominal Aortic Aneurysms
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2023
Source: Arvin H. Soepriatna1, Kelsey A. Bullens2, and Craig J. Goergen1 1 Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 2 Department of Biochemistry, Purdue University, West Lafayette, Indiana Near-infrared fluorescence (NIRF) imaging is an exciting optical technique that utilizes fluorescent probes to visualize complex biomolecular assemblies in tissues. NIRF imaging has many advantages over conventional imaging methods for noninvasive imaging of diseases.
FAQs
Controlling circulation around the diseased segment is central because excision interrupts the aorta’s normal blood-flow pathway. Surgeons must isolate the target region before removing tissue, then restore continuity so blood can pass safely through the repaired vessel. This sequence links the technical success of tissue removal with preservation of effective systemic circulation.
After abnormal tissue is removed, reconstruction is needed to re-establish a continuous aortic pathway. A vascular graft or another repair technique may be selected according to the patient’s condition, rather than applied identically in every case. The choice reflects both the anatomical problem created by excision and the clinical circumstances affecting safe repair.
Outcome depends on several interacting factors identified in the clinical overview: the extent of the aortic disease, the surgical approach, and perioperative cardiovascular management. A larger or more complex abnormal region may create different reconstruction demands than a limited lesion. Care surrounding the operation also contributes to how safely circulation is maintained and recovery proceeds.
The procedure follows a linked sequence: surgeons control circulation around the affected aortic region, remove the targeted abnormal tissue, and reconstruct the vessel so continuity is restored. The repair may use a vascular graft or another technique chosen for the patient’s condition. This workflow combines removal of the problem tissue with immediate restoration of the blood-flow route.
Aortic excision may support treatment of several serious conditions, including aneurysms, severe aortic injury, infection, and selected tumors. These indications differ in cause, but each can involve an abnormal aortic segment requiring removal and repair. The procedure therefore serves more than one clinical purpose, with its role determined by the underlying disease and its extent.
Excised tissue can be submitted for pathological analysis, allowing the removed segment to contribute information about the abnormal process affecting the aorta. This is particularly relevant when the operation addresses infection, a selected tumor, or another uncertain abnormality. Thus, excision can both remove clinically concerning tissue and provide material for medical evaluation of the disease.