Bipolar Contact Lens

A bipolar contact lens is a specialized ophthalmic electrode that records electrical signals from the eye, making it useful for assessing retinal and visual-system function. The lens contains two closely positioned conductive contacts that detect voltage differences generated by light-evoked activity in the retina, producing a localized electroretinographic signal while reducing interference from distant electrical sources. In medicine, bipolar contact lenses support electroretinography and related neurophysiological studies of retinal disorders, optic pathway function, and visual responses. Their direct, minimally invasive interface can improve signal measurement and help researchers and clinicians characterize abnormal ocular electrical activity.

Bipolar Contact Lens - Related Videos

Research

JoVE EoE - Danio rerio (zebrafish)

Eye Lens Dissection: A Technique to Observe Zebrafish Lens Morphology

0 Views •

2023

This video describes the protocol which is developed to dissect adult and larval zebrafish lenses to analyze cortical lens morphology and structural integrity of the lens sutures.

Education

JoVE Core - Introduction to Psychology

Bipolar Disorder

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2025

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.

Imaging Exocytosis in Retinal Bipolar Cells with TIRF Microscopy

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Cited by 18 •

2009

In this video, we demonstrate how to label and visualize single synaptic vesicle exocytosis and trafficking in goldfish retinal bipolar cells using total internal reflectance fluorescence (TIRF) microscopy.

Development of an In Vitro Ocular Platform to Test Contact Lenses

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Cited by 14 •

2016

Current in vitro models for evaluating contact lenses (CLs) and other eye-related applications are severely limited. The presented ocular platform simulates physiological tear flow, tear volume, air exposure and mechanical wear. This system is highly versatile and can be applied to various in vitro analyses with CLs.

Impression Cytology of the Lid Wiper Area

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Cited by 3 •

2016

We collected, stained and imaged cells from the conjunctiva of the inner eyelid margin of human subjects. By characterizing cell morphology and metabolic activity, this method may further our understanding of dry eye and the role that friction between the ocular surfaces may play in perceiving ocular discomfort.

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