Endovascular Exclusion
Endovascular Exclusion - Related Videos
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
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Cited by 3 •
2013
Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion pathobiology.
05:18
Mutual Exclusivity: How Children Learn the Meanings of Words
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2023
Source: Laboratories of Nicholaus Noles and Judith Danovitch—University of Louisville Humans are different from other animals in many ways, but perhaps the most important differentiating factor is their ability to use language. Other animals can communicate and even understand and use language in limited ways, but trying to teach human language to a chimp or a dog takes a great deal of time and effort. In contrast, young humans acquire their native language easily, and they learn linguistic...
03:06
The Pauli Exclusion Principle
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2020
The arrangement of electrons in the orbitals of an atom is called its electron configuration. We describe an electron configuration with a symbol that contains three pieces of information: The number of the principal quantum shell, n, The letter that designates the orbital type (the subshell, l), and A superscript number that designates the number of electrons in that particular subshell. For example, the notation 2p4 indicates four electrons in a p subshell (l = 1) with a principal...
08:08
Simulator Training for Endovascular Neurosurgery
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Cited by 3 •
2020
Simulation of complex, high-risk procedures is critical to the education of medical trainees. A protocol for simulator-based endovascular neurosurgery training in a controlled academic environment is described. The protocol includes stepwise guidelines for trainees of varying levels, with a discussion of the advantages and limitations of this model.
14:58
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
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Cited by 4 •
2017
Surgery is the gold standard for accessible arteriovenious malformations (AVMs), and pre-operative embolization can simplify this procedure. We describe our approach for staged endovascular embolization and open resection of AVMs, and provide a representative clinical example highlighting the advantages of a comprehensively trained neurovascular surgeon leading a multi-disciplinary clinical team.
FAQs
The graft forms a new internal flow channel through the treated vessel segment. Blood travels inside this supported passage instead of directly contacting the abnormal blood-filled segment. By redirecting circulation through the graft, the procedure changes the pressure environment around the aneurysm and supports isolation of the affected region from normal blood flow.
The graft’s sealed ends establish contact with the vessel on either side of the abnormal segment. This prevents blood from entering the aneurysm sac around the repair, which is essential for maintaining exclusion. If blood continues to reach the sac, the intended reduction in pressure and protection from rupture may not be achieved.
Exclusion reduces the aneurysm’s direct exposure to circulating blood and the pressure associated with that flow. Lower pressure within the isolated sac decreases the mechanical stress placed on its abnormal vessel wall. The goal is therefore not simply to cover the aneurysm, but to separate it from the circulation that can contribute to enlargement or rupture.
Endovascular exclusion reaches the affected vessel through catheter-based access rather than requiring the same degree of direct surgical exposure. Because the technique is minimally invasive, it can reduce surgical trauma and shorten recovery time for appropriately selected vascular aneurysms. These advantages must be considered alongside follow-up imaging to evaluate the repair.
Clinicians first guide a catheter through the vasculature toward the abnormal vessel segment. They then position and deploy a covered stent graft so that it spans the affected region and seals at both ends. Once placed, the graft provides the alternate flow channel and isolates the aneurysm sac from direct circulation.
Follow-up imaging assesses whether the graft remains correctly positioned and whether blood can pass through its intended channel. It also evaluates vessel patency, meaning continued openness of the treated passage, and checks for persistent blood flow around the repair. These findings help determine whether exclusion remains effective after the procedure.
The technique is used for selected aneurysms in the aorta and peripheral vessels. Its application depends on whether the abnormal segment can be appropriately isolated with a covered stent graft and whether the resulting repair can maintain vessel flow. In vascular medicine, these uses reflect the broader goal of protecting weakened blood-filled vessel segments from rupture.