Fluoroscopic Image Fusion

Fluoroscopic image fusion is an image-guidance technique that combines real-time X-ray fluoroscopy with previously acquired three-dimensional imaging, such as CT, to provide anatomical context during procedures. It works by registering the 3D dataset to the patient and aligning it with the fluoroscopic view, allowing target structures, vessels, or devices to appear together despite differences in image type and timing. In medicine, this fusion supports interventional radiology, cardiology, and surgery by improving spatial orientation during catheter navigation, device placement, and lesion treatment. Its use can strengthen procedural planning and help clinicians interpret limited two-dimensional fluoroscopic information.

Fluoroscopic Image Fusion - Related Videos

Research

JoVE Journal - Medicine
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X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

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Cited by 2 •

2011

We are developing a dynamic adaptive exposure technique using our scanning beam digital X-ray system. Rather than exposing an object uniformly, the exposure is adapted depending on the opacity of the object. Here we show an experiment on an anthropomorphic phantom that resulted in a dose saving of 30%.

Research

JoVE Journal - Medicine
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Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

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Cited by 4 •

2015

Radiation exposure is an underestimated risk in complex ablation procedures. Here, we describe a protocol to significantly decrease fluoroscopy time and dosage for both the patient and the lab staff by using a novel non-fluoroscopic catheter visualization system.

Research

JoVE Journal - Developmental Biology

Live Imaging of Mouse Secondary Palate Fusion

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Cited by 11 •

2017

Here, we present a protocol for live imaging of mouse secondary palate fusion using confocal microscopy. This protocol can be used in combination with a variety of fluorescent reporter mouse lines, and with pathway inhibitors for mechanistic insight. This protocol can be adapted for live imaging in other developmental systems.

Single-Molecule Imaging to Visualize Fusion Protein Condensates Assembly on DNA Curtains

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2025

This video describes a method to visualize the assembly of fusion protein condensates on DNA molecules at specific loci using single-molecule imaging. These condensates are formed due to LCD-LCD and LCD-DBD interactions, which allow for the recruitment of RNA polymerase II and enhanced gene transcription.

Education

JoVE Core - Chemistry

Nuclear Fusion

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2020

The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons. A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...

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