Hepatic Artery Flush
Hepatic Artery Flush - Related Videos
04:46
Targeting Liver Tumors with Oncolytic Viruses via the Hepatic Artery
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2025
The video demonstrates locoregional delivery of oncolytic viruses through hepatic arterial injection as a therapeutic approach for hepatocellular carcinoma. These viruses selectively replicate in tumor cells, inducing cell lysis and releasing tumor cell-associated antigens. This process triggers immunogenic cell death, inducing an anti-tumor response.
18:47
Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction
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Cited by 22 •
2013
Orthotopic liver transplantation in rats is an indispensable experimental model for biomedical research. Here we present our surgical procedures for orthotopic rat liver transplantation with hepatic arterial reconstruction using a 50% partial graft.
07:08
Assessing and Flushing a Peripheral Intravenous Line
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2023
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT After peripheral intravenous (IV) access is initiated, it is important to assess and maintain the IV catheter according to institutional policies and nursing standards of practice. The regular assessment of the insertion site and the surrounding areas for signs of complications is necessary to prevent IV catheter complications, including infiltration, phlebitis, infection, extravasation, or...
16:19
Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
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Cited by 5 •
2014
Auxiliary liver transplantation provides a temporary support in acute hepatic failure, until regeneration of the failing liver. The heterotopic auxiliary liver transplantation (HALT) with portal vein arterialization (PVA) renders sufficient liver function. We developed an analogous technique in the rat, to examine the influence of the portal vein arterialization on the morphology and function of the graft.
09:02
Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
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Cited by 12 •
2016
In this manuscript, we describe percutaneous isolated hepatic perfusion with simultaneous chemofiltration as treatment for unresectable liver metastases. This procedure is performed under general anaesthesia in the angiosuite by an experienced team, consisting of an interventional radiologist, a clinical perfusionist and anaesthesiologist.
FAQs
Cold preservation solution enters the hepatic artery through a cannula and displaces residual blood and debris throughout the arterial tree. This fluid movement promotes more uniform cooling of the graft while maintaining a clear vascular pathway. The resulting preparation supports subsequent implantation and helps clinicians assess whether arterial flow remains unobstructed.
Controlled pressure allows the solution to move through the arterial tree without relying on uncontrolled force. During perfusion, the response of the vessel can expose resistance or other abnormalities in arterial flow. These observations provide useful information about vessel patency and may help clinicians evaluate the graft before vascular anastomosis.
The cannula provides the access point through which clinicians introduce the cold preservation solution into the hepatic artery. Its placement enables directed perfusion of the vessel and its branches, allowing residual blood and debris to be displaced. This controlled access also makes it possible to observe flow characteristics during graft preparation.
Clinicians may perform the flush before or during liver transplantation, depending on the stage of graft preparation and implantation. The process prepares the arterial pathway before the vascular anastomosis is completed. It can also provide information during the procedure by revealing resistance, abnormal flow, or concerns about vessel patency.
The behavior of the preservation solution during perfusion can reveal resistance or abnormalities in arterial flow. Clinicians can therefore obtain information about whether the vessel remains patent and whether the solution travels through the arterial tree as expected. These observations contribute to assessment of graft quality and readiness for implantation.
By clearing blood and debris, supporting uniform cooling, and preparing the hepatic artery for vascular anastomosis, the technique addresses several practical concerns in graft preparation. Its flow assessment may identify abnormalities before implantation, while the preserved arterial pathway supports a more informed surgical evaluation and contributes to safer transplantation.