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Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction
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Medicine
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JoVE Journal Medicine
Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction

Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction

DOI:
10.3791/4376-v

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18:47 min

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March 07, 2013

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, , ,
1Institute for Laboratory Animal Science and Experimental Surgery,RWTH-Aachen University, 2Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Graduate School of Medicine,Kyoto University

Chapters

  • 00:05Title
  • 01:07Donor Operation
  • 06:30Ex vivo Graft Preparation
  • 10:02Recipient Operation
  • 17:46Results: Survival of Recipient Rats and Hepatocellular Damage to the Liver Grafts
  • 18:24Conclusion

Summary

Automatic Translation

Automatic Translation

Orthotopic liver transplantation in rats is an indispensable experimental model for biomedical research. Here we present our surgical procedures for orthotopic rat liver transplantation with hepatic arterial reconstruction using a 50% partial graft.

Tags

Surgical ProceduresRat ModelPartial Orthotopic Liver TransplantationHepatic Arterial ReconstructionTransplantation ResearchGraft PreservationIschemia-reperfusion InjuryImmunological ResponsesHemodynamicsSmall-for-size SyndromeDifficult Animal ModelMicrosurgical SkillsReliabilityReproducibilityStandardized ProceduresSophisticated ProceduresHepatic Arterial Reconstruction EliminationCuff Anastomosis TechniqueKamada Et Al.Hepatic Rearterialization Elimination

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