Mammary Skin Flap
Mammary Skin Flap - Related Videos
08:18
Engineered Vascularized Muscle Flap
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Cited by 6 •
2016
To date, thick tissue defects are typically reconstructed by applying autologous tissue flaps or engineered tissues. In this protocol, we present a new method for engineering vascularized tissue flap bearing an autologous pedicle, to serve as a substitute to autologous flaps.
03:45
Intraductal Injection: Delivering Injection Mix into the Ducts of the Mouse Mammary Gland
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2023
This video describes an intraductal injection technique where we deliver injection mix into the ducts of mouse mammary glands.
07:57
An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
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2025
This protocol describes the surgical technique for harvesting a human perforator flap model based on the deep inferior epigastric artery pedicle, intended for experimental research.
09:59
Transfer of Mammary Gland-forming Ability Between Mammary Basal Epithelial Cells and Mammary Luminal Cells via Extracellular Vesicles/Exosomes
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Cited by 8 •
2017
This protocol describes methods for purifying, quantitating, and characterizing extracellular vesicles (EVs)/exosomes from non-adherent/mesenchymal mammary epithelial cells and for using them to transfer mammary gland-forming ability to luminal mammary epithelial cells. EVs/exosomes derived from stem-like mammary epithelial cells can transfer this cell property to cells that ingest the EVs/exosomes.
06:30
Intraductal Delivery to the Rabbit Mammary Gland
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Cited by 9 •
2017
Here, we describe a technique for the localized delivery of reagents to the rabbit mammary gland via an intraductal injection. In addition, we describe a protocol for visualization and the confirmation of delivery by high-resolution ultrasound imaging of contrast agents.
FAQs
The flap’s continued connection to feeding vessels supplies oxygen and nutrients after repositioning. This circulation supports tissue survival, wound repair, and healing at the covered defect. If vascular support is maintained, the transferred tissue can remain viable while integration occurs; consequently, vascular preservation is a central consideration when evaluating reconstructive success.
Separating tissue along defined planes helps surgeons mobilize the intended skin and mammary tissue while limiting disruption of the vessels that nourish it. This controlled dissection connects surgical handling with tissue viability: preserving the relevant planes and vascular structures supports predictable repositioning, secure coverage, and continued healing of the repaired area.
A mammary skin flap can provide a controlled setting for examining what happens when tissue receives reduced blood flow and how circulation is restored. Researchers can assess tissue survival and wound repair in relation to ischemia and revascularization, helping them investigate why some reconstructive tissues recover and how surgical strategies may improve viability.
The procedure begins by identifying the tissue to be mobilized and separating it carefully along defined planes. Surgeons preserve its feeding vessels, reposition the mobilized section over the defect, and secure it in place. These steps coordinate tissue movement with vascular protection so circulation can support repair after coverage is completed.
Its principal clinical role is reconstructive coverage of a tissue defect, where available skin and underlying mammary tissue can be repositioned to help restore or protect the affected area. The technique is especially relevant when reconstruction requires living tissue with an intact blood supply, because that circulation supports healing over the repaired defect.
Studies can use these flaps to evaluate tissue viability, wound repair, ischemia, and revascularization. They also provide a way to compare surgical techniques and examine strategies intended to improve soft-tissue reconstruction. Findings may show how well tissue survives after mobilization and whether a chosen approach supports effective healing and vascular recovery.