Myocardial Blood Flow
Myocardial Blood Flow - Related Videos
03:38
Developing a Cerebral Blood Flow Atlas for Blood Flow Mapping
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2025
Source: Tan, Z., et al., Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling. J. Vis. Exp. (2024).This video demonstrates the method to construct a cerebral blood flow atlas by integrating magnetic resonance imaging or MRI-arterial spin labeling data with segmented brain regions, visualizing blood flow patterns, and quantifying flow levels across functional areas.
01:29
Blood Flow
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2025
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow. Slow...
01:17
Autoregulation of Blood Flow
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2024
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls. Chemical Signaling in Autoregulation Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
10:25
Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
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Cited by 9 •
2016
Platelet transfusion and hemostasis was modeled using blood reconstitution and microfluidic flow chambers to investigate the function of blood banking platelets. The data demonstrate the consequences of platelet storage lesion on hemostasis, in vitro.
01:27
Applications of Integration to Find Blood Flow
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2026
Blood flow through a cylindrical blood vessel can be mathematically described using the principles of laminar flow, a regime in which fluid moves smoothly in parallel layers. In this model, the velocity of the blood is not uniform across the cross-section of the vessel; rather, it varies with the radial distance from the center. The maximum velocity occurs along the central axis, decreasing progressively toward the vessel walls, where it reaches zero due to viscous drag.Approximating Blood...
FAQs
Coronary vascular resistance provides the main adjustable control of myocardial blood flow. As cardiac work rises, local metabolites, including adenosine, promote arteriolar dilation and reduce resistance, helping increase delivery to the working myocardium. This response links coronary circulation to metabolic demand rather than relying only on systemic pressure.
Contracting myocardium compresses intramural coronary vessels, so blood passage through the heart muscle occurs mainly during diastole, when contraction has relaxed. This timing distinguishes coronary perfusion from circulation in many other tissues. Evaluating flow therefore requires attention not only to total blood delivery, but also to the phase of the cardiac cycle in which it can occur.
A mismatch between oxygen delivery and myocardial demand can indicate inadequate coronary circulation and contribute to ischemia. Because cardiac work determines how much oxygen the muscle requires, measurements made during increased workload can reveal abnormalities that may not be evident under resting conditions. This demand-sensitive response is central to assessing coronary disease.
Stress assessment examines how myocardial blood flow responds when cardiac work increases. An appropriate response indicates that coronary circulation can adjust delivery to higher metabolic demand, whereas an impaired response may suggest limited coronary reserve or insufficient oxygen delivery. The resulting information helps clinicians investigate ischemia and characterize the functional significance of coronary disease.
Measurements of myocardial blood flow provide information about the adequacy of oxygen delivery to the heart muscle and its change during stress. Clinicians can use these results to support diagnosis of coronary artery disease, estimate risk, and assess whether circulation is sufficient for the patient’s level of cardiac work.
Before and after treatment, myocardial blood flow assessment can show whether coronary circulation has improved and whether delivery better matches myocardial demand. This makes the measurement useful for evaluating interventions intended to restore or improve blood flow. Results can also contribute to follow-up decisions by indicating whether ischemia-related circulatory limitations persist.