Ovarian Volume
Ovarian Volume - Related Videos
04:35
Obtaining Primary Ovarian Cancer Cells from Solid Specimens: A Method to Culture Epithelial Ovarian Cancer Cells from Ovarian Tumor Specimens
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2023
In this video, we describe a method for isolating and characterizing primary ovarian cancer cells from solid ovarian tumor tissue specimens. The epithelial cancer cells obtained using this protocol are suitable for understanding the processes that may lead to ovarian cancer initiation and development.
10:35
An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
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Cited by 18 •
2010
To study in vivo tumor growth and tumor microenvironment, we used a syngeneic and orthotopic mouse model of ovarian cancer in immunocompetent animals. We transduced a mouse tumor cell line (MOV1) with Katushka fluorescent protein (MOV1KAT) and here we show its orthotopic implantation in ovary and in vivo imaging.
09:25
Transplantation Into the Mouse Ovarian Fat Pad
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Cited by 6 •
2016
We describe an ovarian fad pad transplantation assay suitable for studies of normal and transformed epithelia of the female reproductive tract. The mouse fat pad allows transplantation of large tissue fragments, is easily accessible for surgery and imaging, and provides the most favorable native environment for tissues of Müllerian origin.
03:53
Ovarian Fat Pad Transplantation Assay: An In Vivo Technique to Introduce Cells into Ovarian Fat Pad in Mouse Models
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2023
In this video, we demonstrate an assay for transplantation of experimental cells and tissue fragments into the mouse ovarian fat pad. This method can be used to monitor cell regeneration and tumor transformation via non-invasive techniques.
10:41
Culture and Co-Culture of Mouse Ovaries and Ovarian Follicles
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Cited by 17 •
2015
This protocol describes the primary culture/co-culture of mouse ovarian tissue, using ovaries from neonatal mice and individual ovarian follicles from prepubertal mice. The culture techniques support development in a highly physiological manner, allowing investigation of the effect of extrinsic agents on the ovary, and of interactions between ovarian follicles.
FAQs
Ovarian volume must be interpreted in context because expected size varies with age, menstrual status, and the imaging method used. A measurement that appears reduced or enlarged may therefore have different significance in different patients. Clinicians compare the value with other ultrasound findings and the broader clinical picture rather than treating volume as an isolated diagnostic result.
The estimate is derived from three ultrasound dimensions: ovarian length, width, and thickness. These measurements are combined with an ellipsoid formula to represent the ovary as a three-dimensional structure. Small differences in how each dimension is obtained can change the calculated result, which is why consistent measurement technique is important when values are compared between examinations.
Ovarian volume can contribute to assessment of ovarian reserve, meaning the remaining reproductive potential of the ovaries, and may also provide context about follicular activity. It does not establish either feature by itself. Its usefulness increases when interpreted alongside other findings and patient factors, particularly during fertility evaluation or monitoring of reproductive function.
During pelvic ultrasound, the clinician identifies the ovary and records its length, width, and thickness using the selected imaging approach. Those dimensions are entered into an ellipsoid calculation to estimate volume. Repeating the measurements with a standardized technique helps reduce variation and makes changes across follow-up examinations easier to assess.
Serial measurements can help clinicians track whether ovarian size changes over time, particularly when evaluating reproductive or gynecologic health. Comparing examinations is most meaningful when the imaging method and measurement approach remain consistent. Interpretation still requires attention to age, menstrual status, and other imaging findings, because a change in size may not have one universal explanation.
A volume that is larger or smaller than expected can provide a quantitative clue during assessment of ovarian conditions, but it does not identify the cause on its own. Clinicians use the measurement together with other ultrasound observations and patient context. In research, standardized values also support comparisons of ovarian disorders, fertility-related findings, and outcomes across examinations.