Stereotactic Surgical Planning

Stereotactic surgical planning is a precision-based method for locating and targeting structures within the body, especially the brain, using three-dimensional coordinates and medical imaging. It combines MRI or CT data with a stereotactic frame or frameless navigation system to map the target, define a safe trajectory, and account for nearby critical anatomy before surgery. This approach supports procedures such as biopsy, lesion ablation, deep brain stimulation, and targeted drug delivery. By improving spatial accuracy and helping surgeons minimize disruption to healthy tissue, stereotactic planning contributes to safer interventions, more consistent outcomes, and advances in image-guided medicine.

Stereotactic Surgical Planning - Related Videos

Research

JoVE Journal - Medicine
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Stereotactic Radiosurgery for Gynecologic Cancer

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Cited by 14 •

2012

Stereotactic body radiotherapy (SBRT) involves image-guided, ablative radiation delivered to cancer targets refractory to chemotherapy or to conventional radiation treatment. The robotic-armed Cyberknife SBRT system, using sophisticated target localization, delivers hypofractionated radiation doses capable of sterilizing cancer targets. This article will consider new therapeutic roles of SBRT for gynecological cancers.

Research

JoVE Journal - Medicine
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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

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Cited by 9 •

2015

Stereotactic ablative body radiation therapy (SBRT) involves the precise delivery of high-dose radiation to cancer tumor targets. A novel SBRT platform offers a first-of-its-kind gimbaled radiation accelerator mounted within a pivoting O-ring gantry capable of dynamic image-guided tumor tracking. Here, we describe dynamic tumor tracking for lung targets.

Research

JoVE EoE - Neuropathology

A Stereotactically Guided Ablation Technique for Auditory Cortex Removal in Rats

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2025

This video demonstrates a stereotactically-guided surgical procedure for ablating the auditory cortex in a rat. The steps include identifying anatomical landmarks in an anesthetized rat secured in a stereotactic frame, creating a window on the skull above the auditory cortex, aspirating the cortical layers, and providing post-operative care to assess the impact of the ablation on sound processing.

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

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Cited by 3 •

2015

Stereotactic Electroencephalography (SEEG) is an operative technique used in epilepsy surgery to help localize seizure foci. It also affords a unique opportunity to investigate brain function. Here we describe how SEEG can be used to investigate cognitive processes in human subjects.

Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors

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Cited by 15 •

2015

Stereotactic injection of lentiviruses expressing cDNAs or shRNAs can modulate gene expression in specific brain areas of mice. Here, we present a protocol to combine stereotactic injections with behavioral tasks, such as the Open Field Test (OFT) and the Forced Swim Test (FST).

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