Ultrasonic Cardiac Assessment
Ultrasonic Cardiac Assessment - Related Videos
09:25
Assessment of Ultrasonic Vocalizations During Drug Self-administration in Rats
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Cited by 17 •
2010
Drug self-administration and ultrasonic vocalizations (USV) are used as behavioral assessments in animal research, but rarely in combination. The purpose of this article is to describe the advantages of recording USVs during drug self-administration procedures to assess affective responses to drug experience.
10:53
Ultrasonic Assessment of Myocardial Microstructure
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Cited by 10 •
2014
Echocardiography is commonly used to noninvasively characterize and quantify changes in cardiac structure and function. We describe an ultrasound-based imaging algorithm that offers an enhanced surrogate measure of myocardial microstructure and can be performed using open-access image analysis software.
11:10
Respirometric Oxidative Phosphorylation Assessment in Saponin-permeabilized Cardiac Fibers
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Cited by 32 •
2011
Saponin-permeabilized fiber preparation in conjunction with respirometric oxidative phosphorylation analysis provides integrative assessment of mitochondrial function. Mitochondrial respiration in physiological and pathological states can reflect various regulatory influences including mitochondrial interactions, morphology and biochemistry.
05:04
In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter
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Cited by 4 •
2022
We describe here, the establishment and application of an Tg(Myh6-cre)1Jmk/J /Gt(ROSA)26Sortm38(CAG-GCaMP3)Hze/J (referred to as αMHC-Cre/Rosa26A-Flox-Stop-Flox-GCaMP3 below) mouse reporter line for cardiac reprogramming assessment. Neonatal cardiac fibroblasts (NCFs) isolated from the mouse strain are converted into induced cardiomyocytes (iCMs), allowing for convenient and efficient evaluation of reprogramming efficiency and functional maturation of iCMs via calcium (Ca2+) flux.
11:38
Assessment of Cardiac Function and Energetics in Isolated Mouse Hearts Using 31P NMR Spectroscopy
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Cited by 36 •
2010
Langendorff-mode isolated heart perfusion, in conjunction with 31P NMR spectroscopy, combines the fields of biochemistry and physiology into one experiment. The protocol allows for the dynamic measurement of high energy phosphate content and turnover in the heart while concurrently monitoring physiologic function. When performed correctly, this is a valuable technique in the assessment of cardiac energetics.
FAQs
A transducer sends high-frequency ultrasound pulses through the chest and receives echoes as they return from cardiac structures. The system processes these signals into moving images, allowing clinicians to observe the heart during its activity rather than relying only on static anatomy. This real-time display helps evaluate chamber structure, valve appearance, wall motion, and overall pumping performance.
Doppler techniques provide information that imaging alone cannot show by measuring the direction and speed of blood flow. These measurements complement views of the chambers and valves, helping clinicians assess how blood moves through the heart. The combined structural and flow information supports evaluation of cardiac function and the investigation of suspected valve-related abnormalities.
Dynamic imaging shows cardiac structures and motion as the heart beats, so assessment can include wall movement and pumping performance rather than anatomy alone. This temporal information is especially relevant when clinicians need to relate visible motion to overall function. It also makes the examination useful for monitoring changes in cardiovascular conditions over time.
Ultrasonic cardiac assessment provides real-time structural and flow information without ionizing radiation. That distinction makes it valuable when repeated or immediate evaluation is needed, including routine cardiovascular care and emergency medicine. Its usefulness comes from combining a noninvasive approach with direct observation of chambers, valves, wall motion, and blood-flow behavior during the examination.
During an echocardiographic examination, the transducer is placed through the chest to transmit ultrasound pulses and collect returning echoes. The resulting signals are processed into real-time cardiac images, while Doppler measurements can evaluate blood-flow direction and speed. Clinicians use these complementary views to examine both heart structures and functional performance in the same assessment.
The examination can provide information about the heart chambers, valves, wall motion, and pumping performance. Doppler findings add measurements of blood-flow direction and speed, extending the assessment beyond visible anatomy. Together, these outcomes help clinicians characterize structural and functional cardiac findings and support decisions about diagnosis or continued monitoring.
Clinicians use this assessment to support the diagnosis and monitoring of conditions including valve disease, cardiomyopathy, and heart failure. Because it is noninvasive and supplies dynamic information, it fits both routine cardiovascular care and emergency medicine. Its ability to evaluate structure, motion, pumping, and flow makes it relevant when rapid or repeated cardiac assessment is needed.
In research, ultrasonic cardiac assessment offers a way to examine cardiac structure and function while observing movement and blood flow dynamically. The method can contribute information about chambers, valves, wall motion, and pumping performance without ionizing radiation. These characteristics make it useful for investigating cardiovascular findings and for monitoring cardiac conditions in clinical research contexts.