The measured voltage changes arise from coordinated synaptic and neuronal activity in cortical tissue. Electrode placement determines which activity is sampled: surface electrodes support electrocorticographic signals, whereas electrodes within cortical tissue produce intracortical recordings. This distinction lets investigators examine cortical function at different recording locations rather than treating all electrical measurements as equivalent.
Comparing activity across cortical regions or experimental conditions helps link local electrical dynamics with broader brain function. Researchers can examine whether signals differ between regions or when behavioral conditions change, then relate those patterns to sensory processing, motor control, or cognition. Such comparisons are central to interpreting recordings rather than viewing each signal in isolation.
The key difference is electrode location. Surface electrodes are positioned on the cerebral cortex and generate electrocorticographic signals, while intracortical electrodes are placed within cortical tissue. Both approaches measure cortical electrical activity, but they sample it from different anatomical positions, allowing researchers to investigate neural function at the cortical surface or within the tissue.
A basic cortical recording workflow begins by placing electrodes on the cortical surface or within cortical tissue. The electrodes detect voltage changes produced by coordinated neural activity, generating signals such as electrocorticographic or intracortical recordings. Researchers can then compare activity across cortical regions or experimental conditions to relate the measurements to sensory processing, motor control, cognition, or behavior.
Its applications span sensory processing, motor control, cognition, and neurological disorders. By measuring electrical activity from the cortex, researchers can investigate how cortical circuits participate in these functions and how their activity relates to behavior. The approach therefore connects neural measurements with both normal brain operations and changes associated with neurological conditions.
In brain-computer interfaces, cortical signals provide neural input that can be translated into commands. This application uses the relationship between cortical electrical activity and functional brain processes to create an interface based on recorded signals. The same measurements that support studies of cognition or motor control can therefore also contribute to systems that convert cortical activity into control outputs.