Detrusor Opening Pressure

Detrusor opening pressure is the detrusor pressure recorded when urine flow begins, providing a urodynamic measure of how the bladder initiates voiding. During pressure-flow testing, catheters measure vesical and abdominal pressures, and detrusor pressure is calculated as vesical pressure minus abdominal pressure at the onset of flow. The value reflects the interaction between detrusor contractility, urethral outlet resistance, and neural control of micturition. In neuroscience and neuro-urology, it helps characterize bladder dysfunction after spinal cord injury, neurological disease, or other disruptions of lower urinary tract control, supporting diagnosis, treatment planning, and evaluation of functional outcomes.

Detrusor Opening Pressure - Related Videos

Research

JoVE EoE - Urinary Tract Cancer

Detrusor Smooth Muscle Cell Isolation: An Enzymatic Digestion Procedure to Obtain DSM Cells from Human Urinary Bladder Specimens

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2023

In this video, we demonstrate the isolation of detrusor smooth muscle cells from human urinary bladder specimens using a two-step sequential enzymatic treatment.

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

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Cited by 5 •

2013

The laser heated diamond anvil cell combined with synchrotron micro-diffraction techniques allows researchers to explore the nature and properties of new phases of matter at extreme pressure and temperature (PT) conditions. Heterogeneous samples can be characterized in situ under high pressure by 2D mapping and combined powder, single-crystal and multigrain diffraction approaches.

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

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Cited by 2 •

2020

We present a method for establishing a detrusor underactivity model by conus medullaris transection in rats. Detrusor underactivity was successfully stimulated in these animals. The model can be used for studying urinary tract function.

Education

JoVE Core - Chemistry

Vapor Pressure

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2020

When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules move randomly about, they will occasionally collide with the surface of the condensed phase, and in some cases, these collisions will result in the molecules re-entering the condensed phase. The change from the gas phase to the liquid is called condensation. When the rate of condensation becomes equal to the rate of vaporization, neither the amount of the liquid nor the amount of the vapor...

Vapor Pressure Lowering

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2020

The equilibrium vapor pressure of a liquid is the pressure exerted by its gaseous phase when vaporization and condensation are occurring at equal rates: Dissolving a nonvolatile substance in volatile liquid results in a lowering of the liquid’s vapor pressure. This phenomenon can be explained by considering the effect of added solute molecules on the liquid's vaporization and condensation processes. To vaporize, solvent molecules must be present at the surface of the solution. The presence of...

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