Electrode Resistance

Electrode resistance is the opposition an electrode presents to electrical current, a property that influences how accurately neural signals are recorded or delivered. In neuroscience, it arises from the electrode material and geometry, the surrounding electrolyte or tissue, and the electrode–tissue interface, where ionic currents are converted to electronic currents; applying a known current and measuring the resulting voltage provides an estimate through Ohm’s law. Resistance affects thermal noise, signal amplitude, stimulation efficiency, and recording artifacts. Monitoring it helps researchers assess electrode placement and contact quality in extracellular recordings, neural implants, and brain stimulation experiments.

Electrode Resistance - Related Videos

Research

JoVE Journal - Medicine
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Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

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Cited by 5 •

2016

This protocol describes a procedure to track the evolution of mesial network measures in temporal lobe epilepsy (TLE) patients. It is based on the combination of intracranial recordings with a novel numerical technique for data analysis. Specifically, we present a protocol for network analyses of foramen ovale recordings.

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

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Cited by 41 •

2017

This publication describes the fabrication of an organ-on-chip device with integrated electrodes for direct quantification of transendothelial electrical resistance (TEER). For validation, the blood-brain barrier was mimicked inside this microfluidic device and its barrier function was monitored. The presented methods for electrode integration and direct TEER quantification are generally applicable.

Education

JoVE Core - Chemistry

Standard Electrode Potentials

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2020

On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...

Fabrication of Amperometric Electrodes

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Cited by 8 •

2009

This protocol describes how to generate carbon fiber electrodes. The electrodes are subsequently used to detect catecholamine release from vesicles with carbon fiber amperometry.

Patterning Cells on Optically Transparent Indium Tin Oxide Electrodes

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Cited by 1 •

2007

Non-fouling PEG silane monolayer was desorbed from individually addressable ITO electrodes on glass by application of a reductive potential. Electrochemical stripping of PEG-silane layer from ITO microelectrodes allowed for cell adhesion to take place in a spatially defined fashion, with cellular patterns corresponding closely to electrode patterns.

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