Multi-voxel Pattern

A multi-voxel pattern is the distinctive spatial arrangement of activity across many small units, or voxels, in neuroimaging data, providing a way to study information represented by distributed brain networks. In neuroscience, multivariate pattern analysis compares activity values across voxels and uses statistical models or classifiers to identify patterns associated with stimuli, cognitive states, or behavior. Unlike analyses focused on individual regions or average activation, this approach can reveal subtle distributed representations and distinguish conditions with similar overall signal levels. Multi-voxel patterns support research on perception, memory, decision-making, and brain connectivity, while helping link neural activity to cognition and behavior.

Multi-voxel Pattern - Related Videos

Research

JoVE Journal - Neuroscience
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Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

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Cited by 23 •

2014

Informational connectivity measures the correspondence between time courses of multi-voxel information across different brain regions. Multi-voxel pattern discriminability time series are extracted from regions and compared, revealing networks that are not identified in a typical functional connectivity approach.

Research

JoVE EoE - Neuronal Culture Techniques

Constructing Patterned Neuronal Circuits on a Multi-Electrode Array

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2025

This video demonstrates the process of culturing neuronal cells on a patterned multi-electrode array (MEA) to establish modular neuronal networks. This method allows the study of neural signal transmission and cellular interactions.

Education

JoVE Science Education - Psychology

Decoding Auditory Imagery with Multivoxel Pattern Analysis

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2023

Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California Imagine the sound of a bell ringing. What is happening in the brain when we conjure up a sound like this in the "mind's ear?" There is growing evidence that the brain uses the same mechanisms for imagination that it uses for perception.1 For example, when imagining visual images, the visual cortex becomes activated, and when imagining sounds, the auditory cortex is engaged. However, to what extent are...

Research

JoVE Journal - Neuroscience
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Cross-Modal Multivariate Pattern Analysis

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Cited by 5 •

2011

Classical multivariate pattern analysis predicts sensory stimuli a subject perceives from neural activity in the corresponding cortices (e.g. visual stimuli from activity in visual cortex). Here, we apply pattern analysis cross-modally and show that sound- and touch-implying visual stimuli can be predicted from activity in auditory and somatosensory cortices, respectively.

Measuring Grey Matter Differences with Voxel-based Morphometry: The Musical Brain

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2023

Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California Experience shapes the brain. It is well understood that our brains are different as a result of learning. While many experience-related changes manifest themselves at the microscopic level, for example by neurochemical adjustments in the behavior of individual neurons, we may also examine anatomical changes to the structure of the brain at a macroscopic level. One famous example of this kind of change...

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