Addiction Treatment

Addiction treatment comprises medical and behavioral interventions that help people reduce or stop compulsive substance use, manage withdrawal, and sustain recovery. In pharmacology, medications act on receptor and neurotransmitter systems to lessen cravings, blunt drug effects, or stabilize brain signaling during withdrawal, often alongside counseling and social support. These approaches can be adapted to opioids, alcohol, nicotine, and other substance use disorders, with treatment plans guided by clinical assessment, comorbidities, and patient response. By linking drug mechanisms with evidence-based care, addiction treatment supports safer withdrawal management, reduces relapse risk, and provides a framework for evaluating therapeutic targets and improving long-term outcomes.

Addiction Treatment - Related Videos

Research

JoVE EoE - Neurotherapeutics

Deep Brain Stimulation as a Treatment for Drug Addiction in a Rat Model

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2025

Source: Batra, V., et al. A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration. J. Vis. Exp. (2016).This video demonstrates a rat model of drug addiction in which the animal self-administers intravenous methamphetamine by pressing a lever, leading to compulsive drug-seeking behavior driven by dopamine release in the nucleus accumbens. To counteract this, the rat undergoes deep brain stimulation (DBS) via an implanted bipolar...

Education

JoVE Science Education - Psychology

An Introduction to Reward and Addiction

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2023

Consequences play a major role in controlling our behavior. If the consequence is a reward, then it encourages the associated behavior. Rewards can come in many forms such as a pleasant feeling, money, or food. However, sometimes an individual engages in compulsive behavior despite of negative consequences, and this state is known as addiction. Administration of addictive substances is neurochemically rewarding, which ultimately causes a loss of control in limiting the intake. Scientists aim...

Drug Abuse and Addiction: Pharmacological Phenomena

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2024

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

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Cited by 31 •

2015

Here we outline the procedure for MRI-guided repetitive transcranial magnetic stimulation to the dorsomedial prefrontal cortex as an experimental treatment for major depressive disorder.

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

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Cited by 26 •

2013

Psoriasis is a chronic, immune-mediated inflammatory skin disease. The Goeckerman regimen, formulated for the treatment of psoriasis, consists of exposure to ultraviolet B (UVB) light and application of crude coal tar (CCT). The following protocol is for the administration of Goeckerman therapy for the treatment of moderate-to-severe psoriasis.

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