Behavior Modification

Behavior modification is the systematic use of learning principles to change measurable behaviors, making it an important approach in psychology and related health fields. It works by identifying environmental triggers and consequences, then applying conditioning strategies such as positive or negative reinforcement, response cost, and extinction to increase desired behaviors or reduce unwanted ones. Practitioners typically define target behaviors, monitor their frequency, and adjust interventions based on observed outcomes. Applications include classroom management, clinical treatment, behavior therapy, parenting support, and rehabilitation, while careful measurement helps evaluate effectiveness and guide individualized interventions.

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Education

JoVE Core - Introduction to Psychology
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Behavior Modification

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2024

Behavioral approaches have often been criticized for ignoring mental processes and focusing solely on observable behavior. However, these approaches provide an optimistic perspective for individuals seeking to change their behaviors. Rather than concentrating on intrinsic personality traits, behavioral approaches suggest that even longstanding habits can be modified by changing the reward contingencies that maintain them. A real-world application of operant conditioning principles is applied...

Education

JoVE Core - Molecular Biology

Histone Modification

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2020

The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression. Acetylation The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone deacetylase,...

Spreading of Chromatin Modifications

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2020

The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex. Writers The writer is an enzyme that can...

Research

JoVE Journal - Behavior
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Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)

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Cited by 4 •

2015

Prolonged and comprehensive monitoring of mice in a home-cage environment provides a deeper understanding of aberrant behavior in murine models of brain diseases. This paper describes the Integrated Behavioral Station (INBEST) as the key component of contemporary behavioral analysis.

Research

JoVE Journal - Biology
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Detection of Histone Modifications in Plant Leaves

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Cited by 22 •

2011

A reliable and useful approach to detect histone modifications on specific plant genes is described. The approach combines chromatin immunoprecipitation (ChIP) and real-time quantitative PCR. It allows detection of histone modifications on specific genes with a role in diverse physiological processes.

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