Jean-Louis Mege

Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes (URMITE), Aix Marseille Université

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2013

Other Publications

Article	Year
Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification. Infection and immunity\| PubMed ID: 11854238	2002
Systemic endothelial activation is greater in septic than in traumatic-hemorrhagic shock but does not correlate with endothelial activation in skin biopsies. Critical care medicine\| PubMed ID: 11940750	2002
Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12370385	2002
IFN-gamma-induced apoptosis and microbicidal activity in monocytes harboring the intracellular bacterium Coxiella burnetii require membrane TNF and homotypic cell adherence. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12444137	2002
Bartonella quintana bacteremia and overproduction of interleukin-10: model of bacterial persistence in homeless people. The Journal of infectious diseases\| PubMed ID: 12599058	2003
Dysregulation of cytokines in acute Q fever: role of interleukin-10 and tumor necrosis factor in chronic evolution of Q fever. The Journal of infectious diseases\| PubMed ID: 12660942	2003
Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12682255	2003
Whipple's disease: immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens. Human pathology\| PubMed ID: 12827613	2003
Interleukin-4 induces Coxiella burnetii replication in human monocytes but not in macrophages. Annals of the New York Academy of Sciences\| PubMed ID: 12860673	2003
Deactivation of alveolar macrophages in septic neutropenic ARDS. Chest\| PubMed ID: 12907555	2003
Parachlamydia acanthamoebae enters and multiplies within human macrophages and induces their apoptosis [corrected]. Infection and immunity\| PubMed ID: 14500518	2003
Relationship of relapsing hip prosthesis infection by Staphylococcus aureus with gamma interferon deficiency. Journal of clinical microbiology\| PubMed ID: 14605201	2003
Effect of sex on Coxiella burnetii infection: protective role of 17beta-estradiol. The Journal of infectious diseases\| PubMed ID: 14722900	2004
Lipopolysaccharide from Coxiella burnetii is involved in bacterial phagocytosis, filamentous actin reorganization, and inflammatory responses through Toll-like receptor 4. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15004173	2004
Activation and proteasomal degradation of rho GTPases by cytotoxic necrotizing factor-1 elicit a controlled inflammatory response. The Journal of biological chemistry\| PubMed ID: 15152002	2004
Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma. JAMA : the journal of the American Medical Association\| PubMed ID: 15173142	2004
Link between impaired maturation of phagosomes and defective Coxiella burnetii killing in patients with chronic Q fever. The Journal of infectious diseases\| PubMed ID: 15499532	2004
Ectoparasitism and vector-borne diseases in 930 homeless people from Marseilles. Medicine\| PubMed ID: 15643300	2005
Intracellular trafficking of Parachlamydia acanthamoebae. Cellular microbiology\| PubMed ID: 15760458	2005
Lack of microbicidal response in human macrophages infected with Parachlamydia acanthamoebae. Microbes and infection / Institut Pasteur\| PubMed ID: 15826869	2005
IL-16 is critical for Tropheryma whipplei replication in Whipple's disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16177102	2005
Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages. The Journal of infectious diseases\| PubMed ID: 16206080	2005
Antiangiogenic effect of erythromycin: an in vitro model of Bartonella quintana infection. The Journal of infectious diseases\| PubMed ID: 16388485	2006
Whipple's disease: a macrophage disease. Clinical and vaccine immunology : CVI\| PubMed ID: 16467322	2006
TLR2 is necessary to inflammatory response in Coxiella burnetii infection. Annals of the New York Academy of Sciences\| PubMed ID: 16481508	2005
Role for the CD28 molecule in the control of Coxiella burnetii infection. Infection and immunity\| PubMed ID: 16495554	2006
CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells. Molecular biology of the cell\| PubMed ID: 16540523	2006
Deficient transendothelial migration of leukocytes in Q fever: the role played by interleukin-10. The Journal of infectious diseases\| PubMed ID: 16826485	2006
Murine model of infection by Tropheryma whipplei. Infection and immunity\| PubMed ID: 16861681	2006
The two faces of interleukin 10 in human infectious diseases. The Lancet infectious diseases\| PubMed ID: 16931407	2006
Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection. European journal of immunology\| PubMed ID: 17163446	2007
Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever. European cytokine network\| PubMed ID: 17353158	2006
A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus. Microbes and infection / Institut Pasteur\| PubMed ID: 17537665	2007
Increased levels of circulating IL-16 and apoptosis markers are related to the activity of Whipple's disease. PloS one\| PubMed ID: 17551575	2007
Coxiella burnetii infection in C57BL/6 mice aged 1 or 14 months. FEMS immunology and medical microbiology\| PubMed ID: 17555529	2007
Preeclampsia: impaired inflammatory response mediated by Toll-like receptors. Journal of reproductive immunology\| PubMed ID: 18023484	2008
Infection of endothelial cells with virulent Rickettsia prowazekii increases the transmigration of leukocytes. The Journal of infectious diseases\| PubMed ID: 18171297	2008
Persistent Coxiella burnetii infection in mice overexpressing IL-10: an efficient model for chronic Q fever pathogenesis. PLoS pathogens\| PubMed ID: 18248094	2008
Nanobacteria are mineralo fetuin complexes. PLoS pathogens\| PubMed ID: 18282102	2008
Monocyte deactivation in neutropenic acute respiratory distress syndrome patients treated with granulocyte colony-stimulating factor. Critical care (London, England)\| PubMed ID: 18282280	2008
Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages. European journal of immunology\| PubMed ID: 18350541	2008
Rickettsial diseases: from Rickettsia-arthropod relationships to pathophysiology and animal models. Future microbiology\| PubMed ID: 18366341	2008
The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis. PLoS pathogens\| PubMed ID: 18483547	2008
Ameobal pathogen mimivirus infects macrophages through phagocytosis. PLoS pathogens\| PubMed ID: 18551172	2008
Epidemic typhus. The Lancet infectious diseases\| PubMed ID: 18582834	2008
Macrophage polarization in bacterial infections. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18768823	2008
Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease. The Journal of infectious diseases\| PubMed ID: 19222368	2009
New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis. PloS one\| PubMed ID: 19399182	2009
Intracellular life of Coxiella burnetii in macrophages. Annals of the New York Academy of Sciences\| PubMed ID: 19538264	2009
Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis. Blood\| PubMed ID: 19897576	2010
Adipose tissue serves as a reservoir for recrudescent Rickettsia prowazekii infection in a mouse model. PloS one\| PubMed ID: 20049326	2010
Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei. PLoS pathogens\| PubMed ID: 20090833	2010
The transcriptional programme of human heart valves reveals the natural history of infective endocarditis. PloS one\| PubMed ID: 20126625	2010
[Is macrophage polarization the Gordian knot of bacterial infections?]. Médecine sciences : M/S\| PubMed ID: 20132780	2010
Genomic, proteomic, and transcriptomic analysis of virulent and avirulent Rickettsia prowazekii reveals its adaptive mutation capabilities. Genome research\| PubMed ID: 20368341	2010
3D reconstruction of granulomas from transmitted light images implemented for long-time microscope applications. Journal of immunological methods\| PubMed ID: 20561526	2010
Hijacked phagosomes and leukocyte activation: an intimate relationship. Journal of leukocyte biology\| PubMed ID: 20720162	2011
Sex-related differences in gene expression following Coxiella burnetii infection in mice: potential role of circadian rhythm. PloS one\| PubMed ID: 20730052	2010
IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation. PloS one\| PubMed ID: 21042409	2010
Global analysis of circulating immune cells by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. PloS one\| PubMed ID: 21060873	2010
Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response. PloS one\| PubMed ID: 21179488	2010
Macrophage polarization and bacterial infections. Current opinion in infectious diseases\| PubMed ID: 21311324	2011
Circulating matrix metalloproteinases in infective endocarditis: a possible marker of the embolic risk. PloS one\| PubMed ID: 21533198	2011
Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus. PLoS neglected tropical diseases\| PubMed ID: 21610853	2011
An experimental mouse model to establish Tropheryma whipplei as a diarrheal agent. The Journal of infectious diseases\| PubMed ID: 21628657	2011
An evaluation of the effects of Lactobacillus ingluviei on body weight, the intestinal microbiome and metabolism in mice. Microbial pathogenesis\| PubMed ID: 22020311	2012
Effect of rickettsial toxin VapC on its eukaryotic host. PloS one\| PubMed ID: 22046301	2011
The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever. FEMS immunology and medical microbiology\| PubMed ID: 22066909	2012
Effects of Coxiella burnetii on MAPKinases phosphorylation. FEMS immunology and medical microbiology\| PubMed ID: 22092597	2012
Foxp3(+)CD4(+)CD25(+) regulatory T cells are increased in patients with Coxiella burnetii endocarditis. FEMS immunology and medical microbiology\| PubMed ID: 22098165	2012
The gene expression analysis of blood reveals S100A11 and AQP9 as potential biomarkers of infective endocarditis. PloS one\| PubMed ID: 22319637	2012
Defective monocyte dynamics in Q fever granuloma deficiency. The Journal of infectious diseases\| PubMed ID: 22351939	2012
Role of innate and adaptive immunity in the control of Q fever. Advances in experimental medicine and biology\| PubMed ID: 22711637	2012
Immune response and Coxiella burnetii invasion. Advances in experimental medicine and biology\| PubMed ID: 22711638	2012
Cross-protection among Rickettsia species and subspecies in a guinea pig model of cutaneous infection. Comparative immunology, microbiology and infectious diseases\| PubMed ID: 22784931	2012
Whole-cell MALDI-TOF MS: a new tool to assess the multifaceted activation of macrophages. Journal of proteomics\| PubMed ID: 22967923	2012
Overexpression of the Per2 gene in male patients with acute Q fever. The Journal of infectious diseases\| PubMed ID: 22984121	2012
Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments. European journal of cell biology\| PubMed ID: 22999511	2012
Chronic hepatitis E virus infection is specifically associated with an interferon-related transcriptional program. The Journal of infectious diseases\| PubMed ID: 23072754	2013
Orientia tsutsugamushi, the causative agent of scrub typhus, induces an inflammatory program in human macrophages. Microbial pathogenesis\| PubMed ID: 23088884	2013
Impaired stimulation of p38α-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes. Cell host & microbe\| PubMed ID: 23245320	2012
Pathogenic brucellae replicate in human trophoblasts. The Journal of infectious diseases\| PubMed ID: 23303808	2013
Tobacco mosaic virus in the lungs of mice following intra-tracheal inoculation. PloS one\| PubMed ID: 23383021	2013
Monocyte responses in the context of Q fever: from a static polarized model to a kinetic model of activation. The Journal of infectious diseases\| PubMed ID: 23801603	2013
Whole-cell MALDI-TOF mass spectrometry: a tool for immune cell analysis and characterization. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23963939	2013
Placental macrophages are impaired in chorioamnionitis, an infectious pathology of the placenta. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24163411	2013
Evaluation of Current and New Biomarkers in Severe Preeclampsia: A Microarray Approach Reveals theVSIG4 Gene as a Potential Blood Biomarker. PloS one\| PubMed ID: 24349325	2013