Patricia B. Hoyer

Department of Physiology, University of Arizona

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2014

Other Publications

Article	Year
17beta-estradiol affords protection against 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in Fischer-344 rats. Endocrinology\| PubMed ID: 11861533	2002
mdr1a deficiency corrects sterility in Niemann-Pick C1 protein deficient female mice. Molecular reproduction and development\| PubMed ID: 11984826	2002
Expression and activity of microsomal epoxide hydrolase in follicles isolated from mouse ovaries. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 12075107	2002
In vitro ovarian tissue and organ culture: a review. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 12161346	2002
Activation of mitogen-activated protein kinases and AP-1 transcription factor in ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats. Biology of reproduction\| PubMed ID: 12193377	2002
Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 12401505	2002
Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide. Toxicology and applied pharmacology\| PubMed ID: 12408955	2002
Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 12700394	2003
The follicle-deplete mouse ovary produces androgen. Biology of reproduction\| PubMed ID: 14998904	2004
Can the clock be turned back on ovarian aging? Science of aging knowledge environment : SAGE KE\| PubMed ID: 15014203	2004
Initiation of delayed ovotoxicity by in vitro and in vivo exposures of rat ovaries to 4-vinylcyclohexene diepoxide. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 15336714	2004
Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss. Toxicology and applied pharmacology\| PubMed ID: 15710172	2005
Damage to ovarian development and function. Cell and tissue research\| PubMed ID: 15856308	2005
Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15994440	2005
Characterization of cyclicity and hormonal profile with impending ovarian failure in a novel chemical-induced mouse model of perimenopause. Comparative medicine\| PubMed ID: 16422148	2005
Effect of bcl-2 overexpression in mice on ovotoxicity caused by 4-vinylcyclohexene. Toxicology and applied pharmacology\| PubMed ID: 16631218	2006
Effect of duration of dosing on onset of ovarian failure in a chemical-induced mouse model of perimenopause. Menopause (New York, N.Y.)\| PubMed ID: 16735946	2006
Destruction of primordial ovarian follicles in adult cynomolgus macaques after exposure to 4-vinylcyclohexene diepoxide: a nonhuman primate model of the menopausal transition. Fertility and sterility\| PubMed ID: 16952357	2006
Dual modality imaging of a novel rat model of ovarian carcinogenesis. Journal of biomedical optics\| PubMed ID: 16965151	2006
NTP-CERHR expert panel report on the reproductive and developmental toxicity of soy formula. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 16998908	2006
NTP-CERHR expert panel report on the reproductive and developmental toxicity of genistein. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 17186522	2006
involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 17204581	2007
BAX is involved in regulating follicular growth, but is dispensable for follicle atresia in adult mouse ovaries. Reproduction (Cambridge, England)\| PubMed ID: 17244737	2007
Development of an animal model for ovotoxicity using 4-vinylcyclohexene: a case study. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 17342769	2007
Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause. American journal of physiology. Renal physiology\| PubMed ID: 17389681	2007
Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse. Neurobiology of aging\| PubMed ID: 17451844	2008
Involvement of CYP 2E1 enzyme in ovotoxicity caused by 4-vinylcyclohexene and its metabolites. Toxicology and applied pharmacology\| PubMed ID: 17462685	2007
Multidetector computed tomographic morphology of ovaries in cynomolgus macaques (Macaca fascicularis). Journal of the American Association for Laboratory Animal Science : JAALAS\| PubMed ID: 17877330	2007
Effects of impending ovarian failure induced by 4-vinylcyclohexene diepoxide on fertility in C57BL/6 female mice. Comparative medicine\| PubMed ID: 17974126	2007
Drinking water with uranium below the U.S. EPA water standard causes estrogen receptor-dependent responses in female mice. Environmental health perspectives\| PubMed ID: 18087588	2007
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 18348702	2008
Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice. Toxicology and applied pharmacology\| PubMed ID: 18407309	2008
Involvement of the KIT/KITL signaling pathway in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in rats. Biology of reproduction\| PubMed ID: 18448842	2008
Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 18622027	2008
Steroidogenic capacity of residual ovarian tissue in 4-vinylcyclohexene diepoxide-treated mice. Biology of reproduction\| PubMed ID: 18829706	2009
Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system. Toxicology and applied pharmacology\| PubMed ID: 19027032	2009
Serum antimüllerian hormone predicts ovarian reserve in a monkey model. Menopause (New York, N.Y.)\| PubMed ID: 19188851	2009
Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes. Comparative medicine\| PubMed ID: 19295054	2009
Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 19439618	2009
Current methods in investigating the development of the female reproductive system. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19495701	2009
Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries. Toxicology and applied pharmacology\| PubMed ID: 19695275	2009
7,12-dimethylbenz[a]anthracene induces sertoli-leydig-cell tumors in the follicle-depleted ovaries of mice treated with 4-vinylcyclohexene diepoxide. Comparative medicine\| PubMed ID: 20158943	2010
The effect of diet and cardiovascular risk on ovarian aging in cynomolgus monkeys (Macaca fascicularis). Menopause (New York, N.Y.)\| PubMed ID: 20458254	2010
Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary. Toxicology and applied pharmacology\| PubMed ID: 20542051	2010
Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity. Toxicology and applied pharmacology\| PubMed ID: 20816688	2010
Retaining Residual Ovarian Tissue following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice. Journal of osteoporosis\| PubMed ID: 20948577	2010
A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity. Journal of osteoporosis\| PubMed ID: 20948578	2010
Midkine, a heparin-binding protein, is increased in the diabetic mouse kidney postmenopause. American journal of physiology. Renal physiology\| PubMed ID: 21048029	2011
Inhibition of PIK3 signaling pathway members by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biology of reproduction\| PubMed ID: 21076081	2011
Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis. Cancer biology & therapy\| PubMed ID: 21108515	2010
Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis). Comparative medicine\| PubMed ID: 21262124	2010
Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53. Toxicology and applied pharmacology\| PubMed ID: 21262251	2011
4-Vinylcyclohexene diepoxide (VCD) inhibits mammary epithelial differentiation and induces fibroadenoma formation in female Sprague Dawley rats. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 21621605	2011
Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biology of reproduction\| PubMed ID: 21677306	2011
Xenobiotic effects on ovarian preantral follicles. Biology of reproduction\| PubMed ID: 21697514	2011
Ovarian expressed microsomal epoxide hydrolase: role in detoxification of 4-vinylcyclohexene diepoxide and regulation by phosphatidylinositol-3 kinase signaling. Toxicology and applied pharmacology\| PubMed ID: 22061827	2012
4-vinylcyclohexene diepoxide: a model chemical for ovotoxicity. Systems biology in reproductive medicine\| PubMed ID: 22239082	2012
Modeling perimenopause in Sprague-Dawley rats by chemical manipulation of the transition to ovarian failure. Comparative medicine\| PubMed ID: 22776052	2012
Analysis of second-harmonic-generation microscopy in a mouse model of ovarian carcinoma. Journal of biomedical optics\| PubMed ID: 22894485	2012
Glutathione S-transferase class μ regulation of apoptosis signal-regulating kinase 1 protein during VCD-induced ovotoxicity in neonatal rat ovaries. Toxicology and applied pharmacology\| PubMed ID: 23274565	2013
Two-photon excited fluorescence imaging of endogenous contrast in a mouse model of ovarian cancer. Lasers in surgery and medicine\| PubMed ID: 23362124	2013
Postnatal exposure to chromium through mother's milk accelerates follicular atresia in F1 offspring through increased oxidative stress and depletion of antioxidant enzymes. Free radical biology & medicine\| PubMed ID: 23470461	2013
7,12-dimethylbenz[a]anthracene-induced malignancies in a mouse model of menopause. Comparative medicine\| PubMed ID: 23561932	2013
In vivo time-serial multi-modality optical imaging in a mouse model of ovarian tumorigenesis. Cancer biology & therapy\| PubMed ID: 24145178	2014
Xenobiotic effects in the ovary: temporary versus permanent infertility. Expert opinion on drug metabolism & toxicology\| PubMed ID: 24450963	2014
Acute 7,12-dimethylbenz[a]anthracene exposure causes differential concentration-dependent follicle depletion and gene expression in neonatal rat ovaries. Toxicology and applied pharmacology\| PubMed ID: 24576726	2014
Involvement of a volatile metabolite during phosphoramide mustard-induced ovotoxicity. Toxicology and applied pharmacology\| PubMed ID: 24642057	2014