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A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
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Medicine
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A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

DOI:
10.3791/51083-v

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14:26 min

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April 07, 2014

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, , , , , , ,
1Department of Physiology,University of Arizona

Chapters

  • 00:05Title
  • 02:24Treatment with 4-Vinylcyclohexene Diepoxide (VCD)
  • 04:37Voluntary Cage-wheel Exercise
  • 08:36Results: VCD-induced Menopause Treatment Does Not Affect Voluntary or Forced Running Capacity or the Cardiac Adaptive Response to Exercise
  • 13:51Conclusion

Summary

Automatic Translation

Automatic Translation

Two exercise paradigms were tested on a newly developed chemically induced menopausal mouse model to examine the impact of menopause on exercise capacity and cardiac adaption to exercise.

Tags

Keywords: Chemically-induced Ovarian FailureExercise CapacityCardiac AdaptationMenopauseOvariectomized Model4-vinylcyclohexene Diepoxide (VCD)Voluntary Cage-wheel ExerciseForced Treadmill ExerciseCardiovascular Disease (CVD)Endocrine StatePre-menopausePeri-menopausePost-menopause

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