Alain Baulard

Inserm U1019 - CNRS UMR 8024, Université de Lille

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 30	2014

Other Publications

Article	Year
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis. The Biochemical journal\| PubMed ID: 11931640	2002
Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis. The Biochemical journal\| PubMed ID: 11964144	2002
In vivo interaction between the polyprenol phosphate mannose synthase Ppm1 and the integral membrane protein Ppm2 from Mycobacterium smegmatis revealed by a bacterial two-hybrid system. The Journal of biological chemistry\| PubMed ID: 12427759	2003
Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria. The Journal of biological chemistry\| PubMed ID: 12654922	2003
Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis. The Journal of biological chemistry\| PubMed ID: 14559907	2003
EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator. Molecular microbiology\| PubMed ID: 14651620	2004
Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis. Journal of lipid research\| PubMed ID: 15060088	2004
Cloning, expression, and purification of the 27 kDa (MPT51, Rv3803c) protein of Mycobacterium tuberculosis. Protein expression and purification\| PubMed ID: 15177284	2004
Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis. Molecular cell\| PubMed ID: 15494316	2004
[Doping in the peloton of antituberculosis drugs]. Médecine sciences : M/S\| PubMed ID: 15811295	2005
Monitoring of the ethionamide pro-drug activation in mycobacteria by (1)H high resolution magic angle spinning NMR. Biochemical and biophysical research communications\| PubMed ID: 15850780	2005
Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 16243584	2006
Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria. The Journal of antimicrobial chemotherapy\| PubMed ID: 16895935	2006
Ethambutol-induced alterations in Mycobacterium bovis BCG imaged by atomic force microscopy. FEMS microbiology letters\| PubMed ID: 17064372	2006
Chemical force microscopy of single live cells. Nano letters\| PubMed ID: 17850167	2007
Antibody response in pulmonary tuberculosis against recombinant 27kDa (MPT51, Rv3803c) protein of Mycobacterium tuberculosis. Scandinavian journal of infectious diseases\| PubMed ID: 17852894	2007
Direct measurement of hydrophobic forces on cell surfaces using AFM. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 17941657	2007
Organization of the mycobacterial cell wall: a nanoscale view. Pflügers Archiv : European journal of physiology\| PubMed ID: 18043940	2008
Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy\| PubMed ID: 19237648	2009
Molecular mapping of lipoarabinomannans on mycobacteria. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 19278203	2009
Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nature medicine\| PubMed ID: 19412174	2009
Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator. ACS chemical biology\| PubMed ID: 20704273	2010
Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors. Journal of medicinal chemistry\| PubMed ID: 21417236	2011
MALDI imaging techniques dedicated to drug-distribution studies. Bioanalysis\| PubMed ID: 21679033	2011
Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors. Journal of medicinal chemistry\| PubMed ID: 22098589	2012
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic acids research\| PubMed ID: 22156370	2012
Tuberculosis: the drug development pipeline at a glance. European journal of medicinal chemistry\| PubMed ID: 22421275	2012
Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. Journal of medicinal chemistry\| PubMed ID: 22738293	2012
Mechanism of competence activation by the ComRS signalling system in streptococci. Molecular microbiology\| PubMed ID: 23323845	2013
Structural and docking studies of potent ethionamide boosters. Acta crystallographica. Section C, Crystal structure communications\| PubMed ID: 24192167	2013