Priscille Brodin

Inserm U1019 - CNRS UMR 8024, Université de Lille

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 30	2014

Other Publications

Article	Year
Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides. Biochemistry\| PubMed ID: 11814346	2002
Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant. Infection and immunity\| PubMed ID: 12228284	2002
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. Molecular microbiology\| PubMed ID: 12410828	2002
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nature medicine\| PubMed ID: 12692540	2003
CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family. Infection and immunity\| PubMed ID: 14638811	2003
Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex. Microbiology (Reading, England)\| PubMed ID: 14766927	2004
Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6. Infection and immunity\| PubMed ID: 15039340	2004
Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens. The Journal of infectious diseases\| PubMed ID: 15195250	2004
ESAT-6 proteins: protective antigens and virulence factors? Trends in microbiology\| PubMed ID: 15488391	2004
Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 15687025	2005
Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15749894	2005
Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics. Microbiology (Reading, England)\| PubMed ID: 16000731	2005
Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence,... The Journal of biological chemistry\| PubMed ID: 16048998	2005
Tuberculosis: from genome to vaccine. Expert review of vaccines\| PubMed ID: 16117711	2005
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. Infection and immunity\| PubMed ID: 16368961	2006
An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis. Infection and immunity\| PubMed ID: 16552042	2006
Benzofuro[3,2-f][1]benzopyrans: a new class of antitubercular agents. Bioorganic & medicinal chemistry\| PubMed ID: 16616504	2006
High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection. Infection and immunity\| PubMed ID: 16714570	2006
Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence. Journal of bacteriology\| PubMed ID: 16952959	2006
Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues. Bioorganic & medicinal chemistry\| PubMed ID: 17208445	2007
Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva. PLoS medicine\| PubMed ID: 17326707	2007
Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis. PLoS pathogens\| PubMed ID: 17480118	2007
ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity. Journal of bacteriology\| PubMed ID: 17557817	2007
[Aquatic insects and transmission of Mycobacterium ulcerans]. Médecine sciences : M/S\| PubMed ID: 17631825	2007
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP. PLoS pathogens\| PubMed ID: 18282096	2008
Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure. Journal of biomolecular screening\| PubMed ID: 19196705	2009
Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis. Science (New York, N.Y.)\| PubMed ID: 19299584	2009
Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting. Biomaterials\| PubMed ID: 19800113	2010
Systematic genetic nomenclature for type VII secretion systems. PLoS pathogens\| PubMed ID: 19876390	2009
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors. PLoS pathogens\| PubMed ID: 19876393	2009
Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ. Microbiology (Reading, England)\| PubMed ID: 20185505	2010
High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling. PLoS pathogens\| PubMed ID: 20844580	2010
Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors. Journal of medicinal chemistry\| PubMed ID: 21417236	2011
High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery. Future medicinal chemistry\| PubMed ID: 21426019	2010
High-content screening in infectious diseases. Current opinion in chemical biology\| PubMed ID: 21684803	2011
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis. PloS one\| PubMed ID: 22069462	2011
Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors. Journal of medicinal chemistry\| PubMed ID: 22098589	2012
A novel specific edge effect correction method for RNA interference screenings. Bioinformatics (Oxford, England)\| PubMed ID: 22121160	2012
Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. Journal of medicinal chemistry\| PubMed ID: 22738293	2012
The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence. PloS one\| PubMed ID: 23118880	2012
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nature medicine\| PubMed ID: 23913123	2013