Wayne A. Fenton

Department of Genetics, Yale School of Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2014

Other Publications

Article	Year
Folding with and without encapsulation by cis- and trans-only GroEL-GroES complexes. The EMBO journal\| PubMed ID: 12839985	2003
Chaperonin-mediated protein folding: fate of substrate polypeptide. Quarterly reviews of biophysics\| PubMed ID: 14686103	2003
Substrate polypeptide presents a load on the apical domains of the chaperonin GroEL. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15479763	2004
No evidence for a forced-unfolding mechanism during ATP/GroES binding to substrate-bound GroEL: no observable protection of metastable Rubisco intermediate or GroEL-bound Rubisco from tritiu... FEBS letters\| PubMed ID: 15710410	2005
Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation. Cell\| PubMed ID: 15989953	2005
Roles of the N-domains of the ClpA unfoldase in binding substrate proteins and in stable complex formation with the ClpP protease. The Journal of biological chemistry\| PubMed ID: 16207718	2005
GroEL-GroES-mediated protein folding. Chemical reviews\| PubMed ID: 16683761	2006
Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17043235	2006
Disulfide formation as a probe of folding in GroEL-GroES reveals correct formation of long-range bonds and editing of incorrect short-range ones. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17283341	2007
Perturbed ATPase activity and not "close confinement" of substrate in the cis cavity affects rates of folding by tail-multiplied GroEL. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17372195	2007
Two families of chaperonin: physiology and mechanism. Annual review of cell and developmental biology\| PubMed ID: 17489689	2007
Folding trajectories of human dihydrofolate reductase inside the GroEL GroES chaperonin cavity and free in solution. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18093916	2007
Requirement for binding multiple ATPs to convert a GroEL ring to the folding-active state. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19050077	2008
The GroEL/GroES cis cavity as a passive anti-aggregation device. FEBS letters\| PubMed ID: 19577567	2009
Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding. Quarterly reviews of biophysics\| PubMed ID: 19638247	2009
GroEL/GroES cycling: ATP binds to an open ring before substrate protein favoring protein binding and production of the native state. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19915138	2009
ATP-triggered ADP release from the asymmetric chaperonin GroEL/GroES/ADP7 is not the rate-limiting step of the GroEL/GroES reaction cycle. FEBS letters\| PubMed ID: 20083109	2010
Double mutant MBP refolds at same rate in free solution as inside the GroEL/GroES chaperonin chamber when aggregation in free solution is prevented. FEBS letters\| PubMed ID: 21609718	2011
Hydrogen-deuterium exchange in vivo to measure turnover of an ALS-associated mutant SOD1 protein in spinal cord of mice. Protein science : a publication of the Protein Society\| PubMed ID: 21780215	2011
Structure and allostery of the chaperonin GroEL. Journal of molecular biology\| PubMed ID: 23183375	2013
RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse. PloS one\| PubMed ID: 23301088	2013
Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23509252	2013