Wei Zhang
Macromolecules and Interfaces Institute, Virginia Tech
Affiliated withVirginia TechState University of New York College of Nanoscale Science and Engineering (SUNY CNSE)Northwestern University
Research Area
Biography
Dr. Zhang has a unique training background in two disparate fields: DNA repair (PhD) and protein engineering (Postdoc). His PhD work with Dr. Daniel Durocher (Lunenfeld) identified new molecular mechanisms of telomere addition to DNA breaks and the spatial organization of DNA repair. For his postdoc studies with Drs. Sachdev Sidhu and Jason Moffat, Dr. Zhang developed structure-based combinatorial protein engineering approaches to design probes modulating protein-protein interactions. His broad research interests are in the field of ubiquitin signaling, protein engineering, targeted protein degradation, genome stability, and cancer therapeutics (www.thezhanglab.com). In the past three years, his lab has been working on development of synthetic biology approaches to manipulate human cell signal transduction cascades to identify new molecular mechanisms and innovative therapeutic strategies. In recognition of Dr. Zhang’s scientific achievement, he is appointed in the Canadian Institute for Advanced Research (CIFAR) Humans & The Microbiome program as an Azrieli Global Scholar.
JoVE Journal Publications
Article Total : 23 | Year |
|---|---|
 Publication title Cited by 13 | 2014 |
 Publication title Cited by 34 | 2014 |
 Publication title Cited by 5 | 2015 |
 Publication title Cited by 10 | 2016 |
 Publication title Cited by 6 | 2017 |