Karl E. Griswold

Thayer School of Engineering, Dartmouth College

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 21	2014

Other Publications

Article	Year
Effects of codon usage versus putative 5'-mRNA structure on the expression of Fusarium solani cutinase in the Escherichia coli cytoplasm. Protein expression and purification\| PubMed ID: 12509995	2003
pH sensing agar plate assays for esterolytic enzyme activity. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12824584	2003
Enhanced crossover SCRATCHY: construction and high-throughput screening of a combinatorial library containing multiple non-homologous crossovers. Nucleic acids research\| PubMed ID: 14576326	2003
Evolution of highly active enzymes by homology-independent recombination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16009931	2005
Direct selection of trans-acting ligase ribozymes by in vitro compartmentalization. RNA (New York, N.Y.)\| PubMed ID: 16131588	2005
The evolution of catalytic efficiency and substrate promiscuity in human theta class 1-1 glutathione transferase. Journal of molecular biology\| PubMed ID: 17011574	2006
Quantifying and resolving multiple vector transformants in S. cerevisiae plasmid libraries. BMC biotechnology\| PubMed ID: 19930565	2009
Protein fragment swapping: a method for asymmetric, selective site-directed recombination. Journal of computational biology : a journal of computational molecular cell biology\| PubMed ID: 20377457	2010
Optimization algorithms for functional deimmunization of therapeutic proteins. BMC bioinformatics\| PubMed ID: 20380721	2010
Enhanced antimicrobial activity of engineered human lysozyme. ACS chemical biology\| PubMed ID: 20604527	2010
The monoclonal myth. Bioengineered bugs\| PubMed ID: 21326931	2010
Genetically engineered alginate lyase-PEG conjugates exhibit enhanced catalytic function and reduced immunoreactivity. PloS one\| PubMed ID: 21340021	2011
Crystal structure of a charge engineered human lysozyme having enhanced bactericidal activity. PloS one\| PubMed ID: 21408218	2011
Optimization of therapeutic proteins to delete T-cell epitopes while maintaining beneficial residue interactions. Journal of bioinformatics and computational biology\| PubMed ID: 21523929	2011
Optimization of combinatorial mutagenesis. Journal of computational biology : a journal of computational molecular cell biology\| PubMed ID: 21923411	2011
Design and analysis of immune-evading enzymes for ADEPT therapy. Protein engineering, design & selection : PEDS\| PubMed ID: 22898588	2012
Alginate lyase exhibits catalysis-independent biofilm dispersion and antibiotic synergy. Antimicrobial agents and chemotherapy\| PubMed ID: 23070175	2013
Engineering Escherichia coli for soluble expression and single step purification of active human lysozyme. Journal of biotechnology\| PubMed ID: 23220215	2013
Structure-based redesign of proteins for minimal T-cell epitope content. Journal of computational chemistry\| PubMed ID: 23299435	2013
Structure-guided deimmunization of therapeutic proteins. Journal of computational biology : a journal of computational molecular cell biology\| PubMed ID: 23384000	2013
Molecular sensing with magnetic nanoparticles using magnetic spectroscopy of nanoparticle Brownian motion. Biosensors & bioelectronics\| PubMed ID: 23896525	2013
A high-throughput screen for antibiotic drug discovery. Biotechnology and bioengineering\| PubMed ID: 23955804	2013
Bioengineered lysozyme reduces bacterial burden and inflammation in a murine model of mucoid Pseudomonas aeruginosa lung infection. Antimicrobial agents and chemotherapy\| PubMed ID: 23979752	2013
Gene and protein sequence optimization for high level production of fully active and aglycosylated lysostaphin in Pichia pastoris. Applied and environmental microbiology\| PubMed ID: 24561590	2014
Bioengineered lysozyme in combination therapies for Pseudomonas aeruginosa lung infections. Bioengineered\| PubMed ID: 24637705	2014