Joshua J. Breunig

Department of Biomedical Sciences, Cedars-Sinai Medical Center

Affiliated withCedars-Sinai Medical Center University of California, Los Angeles

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 6	2014
Publication title Cited by 2	2023

Other Publications

Article	Year
Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia hypoxia. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 17259645	2007
Glowing green pyramids: a false positive for neocortical neurogenesis reveals a novel neuronal-microglial fusion in the postnatal brain. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17304702	2007
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360686	2007
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nature neuroscience\| PubMed ID: 17589506	2007
Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18077357	2007
The stumpy gene is required for mammalian ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18287022	2008
Everything that glitters isn't gold: a critical review of postnatal neural precursor analyses. Cell stem cell\| PubMed ID: 18371403	2007
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18728187	2008
Decision by division: making cortical maps. Trends in neurosciences\| PubMed ID: 19380167	2009
Profiling identifies precursor suspects: notch family again! Cell stem cell\| PubMed ID: 20452310	2010
Cilia in the brain: going with the flow. Nature neuroscience\| PubMed ID: 20498683	2010
Failed cytokinesis of neural progenitors in citron kinase-deficient rats leads to multiciliated neurons. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 20525772	2011
Not(ch) just development: Notch signalling in the adult brain. Nature reviews. Neuroscience\| PubMed ID: 21505516	2011
Coordinating migratory neuron polarization by numb-ing communication. Developmental cell\| PubMed ID: 21571215	2011
Neural stem cells: historical perspective and future prospects. Neuron\| PubMed ID: 21609820	2011
Development and distribution of neuronal cilia in mouse neocortex. The Journal of comparative neurology\| PubMed ID: 22020803	2012
FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22031906	2011
Basic biology and mechanisms of neural ciliogenesis and the B9 family. Molecular neurobiology\| PubMed ID: 22644387	2012
Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation. Neural development\| PubMed ID: 22776033	2012
Arborization of dendrites by developing neocortical neurons is dependent on primary cilia and type 3 adenylyl cyclase. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23392690	2013
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23575824	2013
Brain injury, neuroinflammation and Alzheimer's disease. Frontiers in aging neuroscience\| PubMed ID: 23874297	2013
T-cell TGF-β signaling abrogation restricts medulloblastoma progression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25082897	2014
Mutations within the pathogenic region of herpes simplex virus 1 gK signal sequences alter cell surface expression and neurovirulence. Journal of virology\| PubMed ID: 25505072	2015
A transposon-mediated system for flexible control of transgene expression in stem and progenitor-derived lineages. Stem cell reports\| PubMed ID: 25702640	2015
Lost highway(s): barriers to postnatal cortical neurogenesis and implications for brain repair. Frontiers in cellular neuroscience\| PubMed ID: 26136658	2015
Ets Factors Regulate Neural Stem Cell Depletion and Gliogenesis in Ras Pathway Glioma. Cell reports\| PubMed ID: 26146073	2015
In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 26666451	2016
Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis. Oncotarget\| PubMed ID: 26760767	2016
Ets Factors Regulate Neural Stem Cell Depletion and Gliogenesis in Ras Pathway Glioma. Cell reports\| PubMed ID: 28009307	2016
BCL6 promotes glioma and serves as a therapeutic target. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28356518	2017
Lethal Giant Lineage Tracing: Mutating Locally, Acting Globally. Neuron\| PubMed ID: 28472645	2017
Tetracycline-Inducible and Reversible Stable Gene Expression in Human iPSC-Derived Neural Progenitors and in the Postnatal Mouse Brain. Current protocols in stem cell biology\| PubMed ID: 28510333	2017
Organoid and Organ-On-A-Chip Systems: New Paradigms for Modeling Neurological and Gastrointestinal Disease. Current stem cell reports\| PubMed ID: 28983454
Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities. Cancer & metabolism\| PubMed ID: 29692895	2018
Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells. Stem cell reports\| PubMed ID: 29706501	2018
In utero electroporation-based translating ribosome affinity purification identifies age-dependent mRNA expression in cortical pyramidal neurons. Neuroscience research\| PubMed ID: 29857015	2019
Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol. Journal of neuroinflammation\| PubMed ID: 30201019	2018
Glioma cell proliferation is enhanced in the presence of tumor-derived cilia vesicles. Cilia\| PubMed ID: 30410731	2018
Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements. Cell\| PubMed ID: 31539496	2019
Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3. Brain : a journal of neurology\| PubMed ID: 33141183	2020
Generation of Murine and Human MADR Recipient Cell Lines for Locus-Specific, Stable Integration of Transgenic Elements. STAR protocols\| PubMed ID: 33377078	2020
Preparation, Assembly, and Transduction of Transgenic Elements Using Mosaic Analysis with Dual Recombinases (MADR). STAR protocols\| PubMed ID: 33377093	2020
A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma. Cancer research\| PubMed ID: 33402390	2021
RELA Fusion-Positive Ependymoma in a Child with Down Syndrome: A Case Report. Pediatric neurosurgery\| PubMed ID: 33690230	2021
discovery of RNA proximal proteins via proximity-dependent biotinylation. RNA biology\| PubMed ID: 34006179	2021
Neurosurgery at the crossroads of immunology and nanotechnology. New reality in the COVID-19 pandemic. Advanced drug delivery reviews\| PubMed ID: 34808227	2022
Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment. Nature communications\| PubMed ID: 34921160	2021
SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances. Journal of experimental & clinical cancer research : CR\| PubMed ID: 35086552	2022
First-line Immune Checkpoint Inhibitor Combinations in Metastatic Renal Cell Carcinoma: Where Are We Going, Where Have We Been? Drugs\| PubMed ID: 35175588	2022
Murine-Derived Glioma Organoids and Cell Line Culture Systems. Current protocols\| PubMed ID: 36744986	2023
Tetracycline-Inducible and Reversible Stable Gene Expression in Human iPSC-Derived Neural Progenitors and in the Postnatal Mouse Brain. Current protocols\| PubMed ID: 37283517	2023